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The evaluation of a positron emission mammography (PEM) system using images co-registered with X-ray mammograms /

X-ray mammography is currently the modality of choice for breast cancer screening. However, X-ray mammography cannot provide a positive diagnosis for cancer. A novel, dedicated breast imaging modality has been developed based on the principles of Positron Emission Tomography (PET). The Positron Emission Mammography (PEM) system is a sensitive, high resolution ($ sp sim2$ mm) breast scanner. PEM detects increased cell metabolism (indicating the presence of cancer) by imaging the distribution of tumour-specific metabolic radiotracers. The accurate co-registration of metabolic and X-ray breast images is important for localizing and characterizing suspicious lesions. Traditionally, registration between different imaging modalities has been difficult. PEM simplifies the image registration process by acquiring an X-ray image and a metabolic image consecutively, without moving the breast between scans. The PEM detectors are integrated into a conventional mammography unit and a co-registration tool has been developed. By providing metabolic information about a suspicious breast lesion, the number of invasive biopsy procedures (currently used to diagnose breast cancer) can be reduced.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.27495
Date January 1997
CreatorsBergman, Alanah M.
ContributorsThompson, C. J. (advisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageMaster of Science (Department of Medical Radiation Physics.)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: 001601785, proquestno: MQ37093, Theses scanned by UMI/ProQuest.

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