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The relationship between dietary omega-3 and omega-6 fatty acid intake and colorectal cancer

<p> Colorectal cancer (CRC) is the fourth leading cause of cancer-related deaths in the United States and the second most expensive. Low compliance with preventive screening predisposes a large portion of the at-risk population to poorer outcomes. Therefore, identification of primary interventions for those not regularly screened for CRC is of utmost importance. Self-reported dietary &omega;-3 and &omega;-6 fatty acid intake were used to determine the cross-sectional relationship with CRC cases (<i>n</i> = 211). Men and women of various ethnic backgrounds (<i>N</i> = 15,178) from the National Health and Nutrition Examination Survey (NHANES), 1999&ndash;2010, were eligible for inclusion in this study. Dietary &omega;-3 intake and the &omega;-3:&omega;-6 ratio were negatively associated with CRC while dietary &omega;-6 intake was positively associated with CRC, for those age 20 to &lt; 50 years, after multivariate adjustment. The Glasgow Prognostic Score was also found to be significantly associated with both dietary &omega;-3 and &omega;-6 intake for all age groups.</p>

Identiferoai:union.ndltd.org:PROQUEST/oai:pqdtoai.proquest.com:1527970
Date14 August 2014
CreatorsKunihiro, Andrew G.
PublisherCalifornia State University, Long Beach
Source SetsProQuest.com
LanguageEnglish
Detected LanguageEnglish
Typethesis

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