Context. Exacerbations of chronic obstructive lung disease (COPD) that result in acute respiratory failure are a significant health care problem with high morbidity and mortality. Recent reports have shown that preventing intubation with the use of non-invasive positive pressure ventilation significantly decreases the morbidity and mortality associated with respiratory failure in this population. / Objective. To evaluate whether patients with COPD and acute respiratory failure treated with non-invasive continuous positive airway pressure (CPAP) have improved clinical outcomes after adjusting for potentially confounding covariates when compared to similar patients who were intubated or treated with medical therapy. / Design and setting. Comparison of three retrospective cohorts, one in which CPAP was routinely available and two in which CPAP were not available for the management of this type of patient. Data were collected on all patients admitted to two ICU's in tertiary care teaching hospitals during the time periods defined by the cohorts. / Population. Two hundred and thirty-eight patients with chronic obstructive lung disease and acute respiratory failure admitted to two intensive care units between January 15th 1985 to December 31st 1995. (Abstract shortened by UMI.)
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.33746 |
| Date | January 2002 |
| Creators | Dial, M. S. (Mary Sandra) |
| Contributors | Menzies, D. (advisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (Department of Epidemiology and Biostatistics.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001864584, proquestno: MQ78863, Theses scanned by UMI/ProQuest. |
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