Two subject groups, seven PPS (4 males, 3 females) and 15 normal controls (9 females, 6 males) were matched on the basis of age, height and weight and participated in this study. Three repeated measurements were conducted to evaluate the reliability of isokinetic measurement of strength (at 4 velocities) and fatigability (25 reciprocal contractions at 3.14 rads.s$ sp{-1}$). Data from two subsequent test days were used to evaluate the fatigue responses of the PPS subjects while ON or OFF pyridostigmine. Significant strength differences were seen between the two groups, however there was no observed difference in the rate of development of fatigue. Reliability of strength was demonstrated for the knee extensors and flexors of the PPS subjects after three consecutive test days. Fatigability of the knee extensors in PPS subjects could be tested reliably after three test days but more time would be required for reliable performance of the knee flexors. Reliability of strength and fatigability was seen for both the knee extensor and flexors of the normal controls after only two consecutive test days. A beneficial effect of the drug on fatigability was not seen in the three female PPS subjects, but was demonstrated in one male subject. The drug appeared to have a beneficial effect on strength in the remaining three male subjects.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.56980 |
| Date | January 1992 |
| Creators | Kilfoil, Monica Rosemonde |
| Contributors | St-Pierre, D. M. (advisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (School of Physical and Occupational Therapy.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001319314, proquestno: AAIMM87721, Theses scanned by UMI/ProQuest. |
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