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Alteraciones hematológicas en trabajadores expuestos ocupacionalmente a mezcla de benceno- tolueno-xileno (btx) en una fábrica de pinturas. / Blood disorders among workers exposed to a mixture of benzene-toluene-xylene (btx) in a paint factory.

Objectives. Evaluate the three blood cell series and identify the presence of hypochromia, macrocytosis, leucopenia, lymphopenia, and thrombocytopenia in a group of workers exposed to the mixture of benzene-toluene-xylene (BTX). Materials and methods. A cross-sectional study which included 97 workers from a paint factory in Mexico. The participants underwent conventional blood count and tests for potential cumulative daily dose of BTX fumes, to estimate exposure. Results. From the total of workers, 19.6% showed macrocytosis, 18.6%, lymphopenia, hypochromia 10.3%, 7.2% and 5.2% thrombocytopenia leukopenia. The crude association of macrocytosis with exposure to high doses of BTX mixture was the only with statistical significance (OR: 3.6, 95% CI 1.08 to 13.9, P = 0.02), and the base for a logistic regression model (OR: 6.7, 95% CI 1.33 to 13.55, P = 0.02) adjusted for age, alcohol consumption, and smoking. Conclusions. All blood cytological components analyzed demonstrated mild changes, potentially associated with exposure to the mixture of BTX. Macrocytosis could constitute an early manifestation worthy for surveillance. / Revisión por pares.

Identiferoai:union.ndltd.org:PERUUPC/oai:repositorioacademico.upc.edu.pe:10757/314358
Date20 March 2014
CreatorsHaro García, Luis, Vélez Zamora, Nadia, Aguilar Madrid, Guadalupe, Guerrero Rivera, Susana, Sánchez Escalante, Vanessa, Muñoz, Sergio R., Mezones Holguín, Edward, Juárez-Pérez, Cuauhtémoc
PublisherInstituto Nacional de Salud (INS)
Source SetsUniversidad Peruana de Ciencias Aplicadas (UPC)
LanguageSpanish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/article
Formatapplication/pdf
SourceUniversidad Peruana de Ciencias Aplicadas (UPC), Repositorio Académico - UPC
Rightsinfo:eu-repo/semantics/openAccess
Relationhttp://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1726-46342012000200003&lng=es&nrm=iso, http://www.ncbi.nlm.nih.gov/pubmed/22858763

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