Submitted by Erika Demachki (erikademachki@gmail.com) on 2014-09-25T17:34:38Z
No. of bitstreams: 2
Dissertação_Lucianna G. N. Lemes.pdf: 2661301 bytes, checksum: c0238e41dfbe2adbd10e5ddcff7a139e (MD5)
license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) / Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2014-09-26T11:31:18Z (GMT) No. of bitstreams: 2
Dissertação_Lucianna G. N. Lemes.pdf: 2661301 bytes, checksum: c0238e41dfbe2adbd10e5ddcff7a139e (MD5)
license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) / Made available in DSpace on 2014-09-26T11:31:18Z (GMT). No. of bitstreams: 2
Dissertação_Lucianna G. N. Lemes.pdf: 2661301 bytes, checksum: c0238e41dfbe2adbd10e5ddcff7a139e (MD5)
license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)
Previous issue date: 2013-12-20 / The calicivirus (norovirus and sapovirus) are important etiologic agents of acute gastroenteritis. Recent studies show that in immunocompromised patients such as those undergoing allogeneic hematopoietic stem cell transplantation (HSCT), norovirus infection can lead to worsening of symptoms and be confused with clinical symptoms of graft versus host disease (GVHD). However, calicivirus screening is not performed, routinely, as part of the patients’ follow-up laboratory exams. The main objective of this study was to evaluate the occurrence of norovirus (NoV) and sapovirus (SaV) in patients who underwent HSCT, and to conduct the molecular characterization of the samples positive for these viruses. Fecal samples were collected weekly, and serum samples were obtained every two weeks of ten patients who underwent HSCT, for a minimum period of five months and a maximum of one year. The secretor status was determined by an enzyme immunoassay and the detection of calicivirus was performed by RT-PCR using primers specific for a partial region of the gene encoding the NoV genogroup I and II (GI and GII) and SaV capsid protein. The genomic sequencing was performed for positive samples. The results showed that from ten patients participating in the study, eight had diarrhea. Among these, six (60%) had positive samples for NoV, and all of them had a secretor phenotype. The duration of NoV excretion in feces ranged from five to 143 days. Viral RNA was also detected in serum specimens, ranging from 29 to 36 days in the five patients infected with NoV. Three of the six patients had acute intestinal GVHD. Through genomic sequencing and phylogenetic analysis all NoV-positive samples were characterized as genotype GI.3, and because they had a high nucleotide identity, they were all characterized as a single haplotype. The data highlight the urgent need of the inclusion of calicivirus screening in the routine testing performed before transplantation and during follow-up of these patients. This is the first report of the occurrence of NoV in patients undergoing HSCT in Brazil. / Os calicivírus (norovírus e sapovírus) são importantes agentes etiológicos da gastroenterite aguda. Estudos recentes mostram que em pacientes imunocomprometidos, como os submetidos a transplante alogênico de células progenitoras hematopoiéticas (TACPH), a infecção por norovírus pode levar ao agravamento dos sintomas e ser confundida com quadro clínico da doença do enxerto contra o hospedeiro (DECH). Entretanto, a triagem para calicivírus não é realizada, rotineiramente, como parte dos exames laboratoriais de acompanhamento destes pacientes. O principal objetivo deste estudo foi avaliar a ocorrência de norovírus (NoV) e sapovírus (SaV) em pacientes que foram submetidos ao TACPH e proceder à caracterização molecular das amostras positivas para estes vírus. Foram obtidas amostras de fezes, coletadas semanalmente, e de soro, a cada quinze dias, de dez pacientes que realizaram o TACPH, por um período mínimo de cinco meses e máximo de um ano. O fenótipo secretor dos pacientes foi determinado utilizando um teste imunoenzimático e a pesquisa de calicivírus foi realizada pela RT-PCR, utilizando-se iniciadores específicos para uma região parcial do gene codificante para a proteína dos capsídeos dos NoV do genogrupo I e II (GI e GII) e dos SaV. Os amplicons das amostras positivas foram submetidos ao sequenciamento genômico e análise filogenética. Os resultados obtidos revelaram que de dez pacientes participantes do estudo, oito apresentaram diarreia e vômito. Dentre esses, seis (60%) apresentaram amostras positivas para NoV, sendo que todos foram identificados como secretores. O período de excreção de NoV nas fezes variou de cinco a 143 dias. Foi também detectado RNA viral nas amostras de soro, variando de 29 a 36 dias, em cinco pacientes infectados por NoV. Três, dos seis pacientes, apresentaram DECH aguda intestinal. Através do sequenciamento genômico e análise filogenética, todas as amostras positivas para NoV, de todos os pacientes, foram caracterizadas como genótipo GI.3 dos NoV, e como foi comprovada elevada identidade nucleotídica entre elas, foram caracterizadas como um único haplótipo. Os dados obtidos ressaltam a urgente necessidade da inclusão da pesquisa de calicivírus na rotina de exames realizados antes do transplante, bem como durante o acompanhamento destes pacientes. Este é o primeiro relato da ocorrência de NoV em pacientes submetidos ao TACPH no Brasil.
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.bc.ufg.br:tede/3177 |
| Date | 20 December 2013 |
| Creators | Lemes, Lucianna Gonçalves Nepomuceno |
| Contributors | Souza, Menira Borges de Lima Dias e, Souza, Menira Borges de Lima Dias e, Fiaccadori, Fabíola Souza, Leite, José Paulo Gagliardi |
| Publisher | Universidade Federal de Goiás, Programa de Pós-graduação em Biologia das Interações PH (IPTSP), UFG, Brasil, Instituto de Ciências Biológicas - ICB (RG) |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | Portuguese |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da UFG, instname:Universidade Federal de Goiás, instacron:UFG |
| Rights | http://creativecommons.org/licenses/by-nc-nd/4.0/, info:eu-repo/semantics/openAccess |
| Relation | 6367159433410056917, 600, 600, 600, -3872772117827373404, -203884118251241698, Adler JL, Zickl R. Winter vomiting disease. J Infect Dis 119: 668-673, 1969. Alkhouri N, Danziger-Isakov L. Norovirus and severe chronic gastroenteritis in pediatric stem cell transplantation: The plot thickens. Pediatric Transplant 15: 671-672, 2011. Andreasi MSA, Cardoso DDP, Fernandes SM, Tozetti IA, Borges AMT, Fiaccadori FS, Santos RAT, Souza M. Adenovirus, calicivirus and astrovirus detection in fecal samples of hospitalized children with acute gastroenteritis from Campo Grande, Brazil. Mem Inst Oswaldo Cruz 103: 741-744, 2008. Ariza-Heredia EJ, Nesher L, Chemaly RF. Cytomegalovirus diseases after hematopoietic stem cell transplantation: A mini-review. Cancer Lett 342(1): 1-8, 2013. Atmar RL, Estes MK. Diagnosis of noncultivatable gastroenteritis viruses, the human caliciviruses. Clin Microbiol Rev 14: 15-37, 2001. Atmar RL, Opekun AR, Gilger MA, Estes MK, Crawford SE, Neill FH, Graham DY. Norwalk virus shedding after experimental human infection. Emerg Infect Dis 14: 1553-1557, 2008. Atmar RL, Bernstein DI, Harro CD, Al-Ibrahim MS, Chen WH, Ferreira J, Estes MK, Graham DY, Opekun AR, Richardson C, Mendelman PM. Norovirus vaccine against experimental human Norwalk Virus illness. N Engl J Med 365: 2178-21787, 2011. Azevedo W & Ribeiro MC. Fontes de Células Tronco- Hematopoiéticas para Transplantes. Med 33: 381-389, 2000. Balman FF, Vaz RS, Fernandes A, Guimarães AT. Transplante de células tronco hematopoiéticas alogênico e doença do enxerto contra o hospedeiro aguda (DECHa): uma revisão de profilaxia e tratamento. Rev Bras Alerg Imunopatol 32: 211-216, 2009. Bernard H, Höhne M, Niendorf S, Altmann D, Stark K. Epidemiology of norovirus gastroenteritis in Germany 2001-2009: eight seasons of routine surveillance. Epidemiol Infect 21:1-12, 2013. Bok K, Green KY. Norovirus gastroenteritis in immunocompromised patients. N Engl J Med 367: 2126-2132, 2012. Borges, AM, Teixeira J.M, Costa PS, Giugliano LG, Fiaccadori FS, Franco C, Brito WM, Leite JP, Cardoso DD. Detection of calicivirus from fecal samples from children with acute gastroenteritis in the West Central region of Brazil. Mem Inst Oswaldo Cruz 101: 721-724, 2006. 58 Bruin E, Duizer E, Vennema H, Koopmans MP. Diagnosis of Norovirus outbreaks by commercial ELISA or RT-PCR. J Virol Methods 137: 259-264, 2006. Burton-MacLeod JA, Kane EM, Beard RS, Hadley LA, Glass RI, Ando T. Evaluation and comparison of two commercial enzyme-linked immunosorbent assay kits for detection of antigenically diverse human noroviruses in stool samples. J Clin Microbiol 42: 2587-2595, 2004. Cannon JL, Papafragkou E, Park GW, Osborne J, Jaykus LA, Vinjé J. Surrogates for the study of norovirus stability and inactivation in the environment: a comparison of murine norovirus and feline calicivirus. J Food Prot 69(11): 2761-2765, 2006. Castagnola E, Faraci M, Moroni C, et al. Rare viral infections in children receiving hemopoietic stem cell transplant. Bone Marrow Transplant 41(Suppl 2): S100-S103, 2008. Center for International Blood and Marrow Transplant Research (CIBMTR). Disponível em: http://www.cibmtr.org/pages/index.asp. Acesso em: 28/11/2013. Chang YJ, Weng CL, Sun LX, Zhao YT. Allogeneic bone marrow transplantation compared to peripheralblood stem cell transplantation for the treatment of hematologic malignancies: a meta-analysis based on time-to-event data from randomized contolled trials. Ann Hematol 91: 427-437, 2012. Cheetham S, Souza M, Meulia T, Grimes S, Han MG, Saif LJ. Pathogenesis of a genogroup II human norovirus in gnotobiotic pigs. J Virol 80(21): 10372-10381, 2006. Chehade H, Girardin E, Delich V, Pascual MA, Venetz JP, Cachat F. Acute norovirus-induced agranulocytosis in a pediatric Kidney transplant recipiente. Transpl Infect Dis 14: 27-29, 2012. Chen SC, Tan LB, Huang LM, Chen KT. Rotavirus infection and the current status of rotavirus vaccines. J Formos Med Assoc 111:183-193, 2012. Chen SY, Chiu CH. Worldwide molecular epidemiology of norovirus infection. Paediatr Int Child Health 32(3): 128-131, 2012. Chiba S, Sakuma Y, Kogasaka R, Akihara M, Horino K, Nakao T, Fukui S. An outbreak of gastroenteritis associated with calicivirus in an infant home. J. Med Virol 4: 249-254, 1979. Clarke IN & Lambden PR. Organization and expression of calicivirus genes. J Infect Dis 181: S309-S316, 2000. 59 Dai YC, Hu GF, Zhang XF, Song CL, Xiang WL, Wu XB, Wang LY, Jiang X, Nie J. Molecular epidemiology of norovirus gastroenteritis in children in Jiangmen, China, 2005-2007. Arch Virol 156: 1641-1646, 2011. Danial J, Cepeda JA, Cameron F, Cloy K, Wishart D, Templeton KE. Epidemiology and costs associated with norovirus outbreaks in NHS Lothian, Scotland 2007-2009. J Hosp Infect 79: 354-358, 2011. Danziger-Isakov L. Gastrointestinal infections after transplantation. Curr Opin Gastroenterol 30: 1-7, 2013. De Benedictis P, Schultz-Cherry S, Burnham A, Cattoli G. Astrovirus infections in humans and animals - molecular biology, genetic diversity, and interspecies transmissions. Infect Genet Evol 11(7): 1529-44, 2011. De Oliveira DMM, Souza M, Fiaccadori FS, Santos HCP, das Dôres DPC. Monitoring of Calicivirus among day-care children: Evidence of asymptomatic viral excretion and first report of GI.7 norovirus and GI.3 sapovirus in Brazil. J Med Virol, 2013. Debbink K, Lindesmith LC, Donaldson EF, Baric RS. Norovirus Immunity and the Great Escape. PLoS One 8: 1-5, 2012. Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention. Updated norovirus outbreak management and disease prevention guidelines. MMWR Recomm Rep 60: 1-18, 2011. Doane FW. Electron microscopy for the detection of gastroenteritis viruses. In: Kapikian AZ. Viral infections of the gastrointestinal tract. Marcel Dekker, New York, 1994. Dolin R, Blacklowi NR, Dupont H, Buscho RF, Wyatt RG, Kasel JA, Hornick R, Chanock RM. Biological properties of Norwalk agent of acute infectious nonbacterial gastroenteritis. Proc Soc Exp Biol Med 140: 578-583, 1972. Donaldson EF, Lindesmith LC, Lobue AD, Baric R. No pathogenesis: mechanisms of persistence and immune evasion in human populations. J compilat 225: 190-211, 2008. Donaldson EF, Lindesmith LC, Lobue AD, Baric R. Viral shape-shifting: norovirus evasion of the human immune system. Nature Rev Microb 8: 231-241, 2010. Doshi M, Woodwell S, Kellerher K, Mangan K, Axelrod P. An outbreak of norovírus infection in a bone marrow transplant unit. Am J Inf Con 41: 820-823, 2013. Duizer E, Bijkerk P, Rockx B, Groot A, Twisk F, Koopmans M. Inactivation of Caliciviruses. Appl. Environ. Microbiol 70: 4538-4543, 2004. 60 Duizer E, Schwab KJ, Neill FH, Atmar RL, Koopmans MP, Estes MK. Laboratory efforts to cultivate noroviruses. J Gen Virol 85: 79-87, 2004. Ebdrup L, Böttiger B, Mølgaard H, Laursen AL. Devastating diarrhoea in a heart-transplanted patient. J Clin Virol 50: 263-265, 2010. Edward A, Copelan MD. Hematopoietic Stem-Cell Transplantation. N Engl J Med 354:1813-1826, 2006. Fankhauser RL, Monroe SS, Noel JS, Humprey CD, Bresee JS, Parashar UD, Ando T, Glass RI. Epidemiologic and molecular trends of Norwalk-like viruses associated with outbreaks of gastroenteritis in the United States. J Infect Dis 186: 1-7, 2002. Fastier LB. A new feline virus isolated in tissue culture. Am J Vet Res 18, 382-389, 1957. Ferreira MS, Xavier MP, Fumian TM, Victoria M, Oliveira SA, Pena LH, Leite JP, Miagostovich MP. Acute gastroenteritis cases associated with noroviruses infection in the state of Rio de Janeiro. J Med Virol 80: 338-344, 2008. Ferreira MSR, Xavier MP, Tinga AC, Rose TL, Fumian TM, Fialho AM, Assis RM, Costa FA, Oliveira SA, Leite JP, Miagostovich MP. Assessment of Gastroenteric Viruses Frequency in a Children’s Day Care Center in Rio De Janeiro, Brazil: A Fifteen Year Study (1994–2008). PLoS One 7: 1-7, 2012. Frange P, Touzot F, Debré M, Héritier S, Leruez-Ville M, Cros G, Rouzioux C, Blanche S, Fischer A, Avettand-Fenoël V. Prevalence and clinical impact of norovirus fecal shedding in children with inherited immune deficiencies. J Infect Dis 206: 1269-1274, 2012. Fumian TM, Justino MC, D'Arc JPM, Reymão TK, Abreu E, Soares L, Linhares AC, Gabbay YB. Quantitative and molecular analysis of noroviruses RNA in bloo d from children hospitalized for acute gastroenteritis in Belém, Brazil. J Clin Virol 58(1): 31-35, 2013. Gallimore CI, Cubitt D, du Plessis N, Gray JJ. Asymptomatic and symptomatic excretion of noroviruses during a hospital outbreak of gastroenteritis. J Clin Microbiol 42: 271-274, 2004. Garcia C, Dupont HL, Long KZ, Santos JI, Ko G. Asymptomatic norovirus infection in Mexican children. J Clin Microbiol 44: 2997-3000, 2006. George S, Menon VK, Ramani S, Kang G. Comparison of primers for the detection of genogroup II noroviruses in India. Indian J Med Microbiol 30: 24-29, 2012. 61 Glass RJ, White LJ, Ball JM, Lepare-Goffart I, Hardy ME, Estes MK. Norwalk virus open reading frame 3 encodes a minor structural protein. J Virol 74: 6581-6591, 2000. Green KY, Ando T, Balayan MS, Berke T, Clarke IN, Estes MK, Matson DO, Nakata S, Neill JD, Studdert MJ, Thiel HJ. Taxonomy of the caliciviruses. J Infect Dis 181: 322-330, 2000. Green KY. Caliciviridae: the noroviruses. In: Knipe DM, Howley PM, Fields virology, Philadelphia: Lippincott Williams & Wilkins, p. 949-979, 2007. Green MR & Sambrook J. Molecular cloning: a Laboratory Manual. Cold Spring Harbor Laboratory, New York p. 26-27, 2012. Greenberg HB, Wyatt RG, Kalica AR, Yolken RH, Black R, Kapikian AZ, Chanock RM. New insights in viral gastroenteritis. In: Pollard M, ed. Perspectives in virology. Vol XI. New York: Alan Liss, p. 163-187, 1981. Hardy ME. Norovirus protein structure and function. FEMS Microbiol. Lett 253: 1- 8, 2005 Harris JP, Lopman BA, Cooper BS, O’Brien SJ. Does spatial proximity drive norovírus transmission during outbreaks in hospitals? BMJ Open 3: e003060, 2013. Hutson AM, Atmar RL & Estes MK. Norovirus disease: changing epidemiology and host susceptibility factors. Trends in Microbiol 12: 279-287, 2004. ICTV dB Management (2012). Caliciviridae. In: ICTVdB - The Universal Virus Database, version 3. Büchen-Osmond, C. (Ed), Columbia University, New York, USA 2012, International Committee on Taxonomy of Viruses (ICTV). Jiang X, Wang M, Wang K, Estes MK. Sequence and genomic organization of Norwalk virus. Virology 195: 51-61, 1993. Jiang X, Huang PW, Zhong WM, Farkas T, Cubitt DW & Matson DO. Design and evolution of a primer pair that detects both norwalk-like and sapporo-like caliciviruses by RT-PCR. J Virological Methods 83: 145-154, 1999. Kapikian AZ, Wyatt RG, Dolin R, Thornhill TS, Kalica AR, Chanock RM. Visualization by immune electron microscopy of a 27-nm particle associated with acute infectious nonbacterial gastroenteritis. J Virol 10: 1075-1081, 1972. Kapikian AZ, Gerin JL, Wyatt RG, Thornhill TS, Chanock RM. Density in cesium chloride of the 27 nm "8FIIa" particle associated with acute infectious nonbacterial gastroenteritis: determination by ultra-centrifugation and immune electron microscopy. Proc Soc Exp Biol Med 42: 874-877, 1973. 62 Kaplan JE, Gary GW, Baron RC, Singh N, Schonberger LB, Feldman R & Greenber HB. Epidemiology of Norwalk gastroenteritis and the role of norwalk virus in outbreaks of acute nonbacterial gastroenteritis. Ann Int Med 96: 756-761, 1982. Khamrin P, Nguyen TA, Phan TG, Satou K, Masuoka Y, Okitsu S, Maneekarn N, Nishio O, Ushijima H. Evaluation of immunochromatography and commercial enzyme-linked immunosorbent assay for rapid detection of norovírus antigen in stool samples. J Virol Methods 147: 360-363, 2008. Khamrin P, Takanashi S, Chan-It W, Kobayashi M, Nishimura S, Katsumata N, Okitsu S, Maneekarn N, Nishio O, Ushijima H. Immunochromatography test for rapid detection of norovirus in fecal specimens. J Virol Methods 157: 219-222, 2009. Kim MJ, Kim YJ, Lee JH, Lee JS, Kim JH, Cheon DS, Jeong HS, Koo HH, Sung KW, Yoo KH, Choe YH. Norovirus: A Possible Cause of Pneumatosis Intestinalis. Pediatr Gastroenterol Nutr 52: 314-318, 2011. Kittigul L, Panjangampatthana A, Pombubpa K, Taweekate Y, Pungchitton S, Diraphat P, Siripanichgon K.Detection and genetic characterization of norovirus in environmental water samples in Thailand. Southeast Asian J Trop Med Public Health 43: 323-332, 2012. Kojima S, Kageyama T, Fukushi S, Hoshino FB, Shinohara M, Uchida K, Natori K, Takeda N, Katayama K. Genogroup-specific PCR primers for detection of Norwalk-like viruses. J Virol Methods 100: 107-114, 2002. Koopmans M, Duizer E. Foodborne viruses: an emerging problem. Int J Food Microbiol 90: 23-41, 2004. Koopmans M. Progress in understanding norovirus epidemiology. Curr Opin Infect Dis 21: 544-552, 2008. Larsson MM, Rydell GE, Grahn A, Rodriguez- Diaz J, Akerlind B, Hutson AM, Estes MK, Larson G, Svensson L. Antibody Prevalence and Titer to Norovirus (Genogroup II) Correlate with Secretor (FUT2) but Not with ABO Phenotype or Lewis (FUT3) Genotype. J Infect Dis 194: 1422-1427, 2006. Lee C, Cheong S, Lee HJ, Kwon M, Kang I, Oh EG, Yu HS, Shin SB, Kim SJ. Evaluation of the sensitivity and specificity of primer pairs and the efficiency of RNA extraction procedures to improve noroviral detection from oysters by nested reverse transcription-polymerase chain reaction. J Microbiol 48: 586-593, 2010. Li J, Predmore A, Divers E, Lou F. New Interventions against human norovirus: progress, opportunities, and challenges. Annu Rev Food Sci Technol 3: 331-352, 2012. 63 Liakopoulou E, Mutton K, Carrington D, Robinson S, Steward CG, Goulden NJ, Cornish JM, Marks DI. Rotavirus as a significant cause of prolonged diarrhoeal illness and morbidity following allogeneic bone marrow transplantation. Bone Marrow Transplant 36(8): 691-694, 2005. Lindesmith L, Moe C, Marionneau S, Ruvoen N, Jiang X, Lindblad L, Stewart P, Lependu J, Baric R. Human susceptibility and resistance to Norwalk virus infection. Nat Med 9: 548-553, 2003. Lindesmith L, Moe C, LePendu, J, Frelinger JA, TreanorJ, Baric RS. Cellular and Humoral Immunity following Snow Mountain Virus Challenge. J Virol 79(5): 2900-2909, 2005. Lindesmith LC, Donaldson EF, Lobue AD, Cannon JL, Zheng DP, Vinje J, Baruc R. S. Mechanisms of GII.4 norovirus persistence in human populations. PLoS Med 5: 269-290, 2008. Lindesmith LC, Debbink K, Swanstrom J, Vinje J, Costantini V, Baric RS, Donaldson EF. Monoclonal antibody-based antigenic mapping of norovírus GII.4. J Virol 86: 873-883, 2012. Lindesmith LC, Beltramello M, Eric FD, Corti D, Swanstrom J, Debbink K, Lanzavecchia A, Baric RS. Immunogenetic Mechanisms Driving Norovirus GII.4 Antigenic Variation. PlosPathogens 8: e1002705, 2012. Liu P, Yuen Y, Hsiao HM, Jaykus LA, Moe C. Effectiveness of liquid soap and hand sanitizer against Norwalk virus on contaminated hands. Appl Environ Microbiol 76: 394-399, 2010. Macinga DR, Sattar SA, Jaykus LA, Arbogast JW. Improved inactivation of nonenveloped enteric viruses and their surrogates by a novel alcohol-based hand sanitizer. Appl Environ Microbiol 74(16): 5047-5052, 2008. Marionneau S, Cailleau- Thomas A, Rocher J, Le Moullac-Vaidye B, Ruvoen N, Clément M, Le Pendu J. ABH and Lewis histo- blood group antigens, a model for the meaning of oligosaccharide diversity in the face of a changing world. Biochimie 83: 565-573, 2001. Marionneau S, Ruvoen N, Le Moullac- Vaidye B, Clément M, Cailleau-Thomas, A, Ruitz- Palacois G, Huang P, Jiang X, Le Pendu J. Norwalk virus binds to histo- blood groups antigens present on gastroduodenal epithelial cells of secretor individuals. Gastroenterol 122: 1967-1977, 2002. Marks PJ, Vipond IB, Carlisle D, Deakin D, Fey RE, Caul EO. Evidence for airborne transmission of Norwalk-like virus (NLV) in a hotel restaurant. Epidemiol Infect 124: 481-487, 2000. Marks PJ, Vipond IB, Regan FM, Wedgwood K, Fey RE, Caul E. O. A school outbreak of Norwalk-like virus: Evidence for airborne transmission. Epidemiol Infect 131: 727-736, 2003. 64 Matsui SM & Greenberg HB. Immunity to calicivirus infection. J Infect Dis 181: 331-335, 2000. Matthews RE. Classification and nomenclature of viruses. Intervirol 12: 129-296, 1979. Matthews JE, Dickey BW, Miller RD, Felzer JR, Dawson BP, Lee AS, Rocks JJ, Kiel J, Montes JS, Moe CL, Eisenberg JN, Leon JS. The epidemiology of published norovirus outbreaks: a review of risk factors associated with attack rate and genogroup. Epidemiol Infect 140(7): 1161-1172, 2012. Mitchell DK, Monroe SS, Jiang X, Matson DO, Glass RI, Pickering LK. Virologic features of an astrovirus diarrhea outbreak in a day care center revealed by reverse transcriptase-polymerase chain reaction. J Infect Dis 172: 1437-1444, 1995. Morillo SG, Luchs A, Cilli A, Ribeiro CD, Calux SJ, Carmona Rde C, Timenetsky Mdo C. Large gastroenteritis outbreak due to norovirus GII in São Paulo, Brazil, summer 2010. Rev Inst Med Trop Sao Paulo 53: 119-120, 2011. Morter S, Bennet G, Fish J, Richards J, Allen DJ, Nawaz S, Iturriza-Gómara M. Norovirus in the hospital setting: virus introduction and spread within the hospital environment. J Hosp Infec 77: 106-112, 2011. Mounts AW, Ando T, Koopmans M, Gallimore C, Adak GK, Gray JJ, Brown DW. Could weather seasonanlity of gastroenteritis associated with Norwalk-like viruses. J Infect Dis 181: S284-S287, 2000. Munir N, Liu P, Gastañaduy P, Montes J, Shane A, Moe C. Norovirus infection in immunocompromised children and children with hospital-acquired acute gastroenteritis. J Med Virol, 2013. Nelson AM, Walk ST, Taube S, Taniuchi M, Houpt ER, Wobus CE, Young VB. Disruption of the human gut microbiota following Norovirus infection. PLoS One 7(10): e48224, 2012. Nenonem NP, Hannoun C, Larsson CU, Bergstrom T. Marked genomic diversisty of norovirus genogroup I strains in a waterborne outbreak. Appl Environ Microbiol 78(6):1846-1852, 2012 Nguyen TA, Khamrin P, Takanashi S, Le Hoang P, Le Pham D, Hoang KT, Satou K, Masuoka Y, Okitsu S, Ushijima H. Evaluation of immunochromatography tests for detection of rotavirus and norovirus among Vietnamese children with acute gastroenteritis and the emergence of a novel norovirus GII.4 variant. J Trop Pediatr 53: 264-269, 2007. 65 Nordgren J, Nitiema LW, Ouermi D, Simpore J, Svensson L. Host genetic factors affect susceptibility to Norovirus infections in Burkina Faso. Plos One 8: 1-10, 2013. Oka T, Mori K, Iritani N, Harada S, Ueki Y, Iizuka S, Mise K, Murakami K, Wakita T, Katayama K. Human sapovirus classification based on complete capsid nucleotide sequences. Arch Virol 157: 349-52, 2012. Oriol R, Candellier JJ & Mollicone R. Molecular genetics of H. Vox Sang 78: 105-108, 2000. Papafragkou E, Hewitt J, Park GW, Greening G, Vinjé J. Challenges of Culturing Human Norovirus in Three-Dimensional Organoid Intestinal Cell Culture Models. PLoS ONE 8(6): 1-7, 2013. Parashar U, Quiroz ES, Mounts AW, Monroe SS, Fankhauser RL, Ando T, Noel JS, Bulens SN, Beard SR, Li JF, Bresee JS, Glass RI. “Norwalk-like viruses”: Public health consequences and outbreak management. MMWR Morb Mortal Wkly Rep 50: 1-17, 2001. Parra GI, Bok K, Taylor R, Haynes JR, Sosnovtsev SV, Richardson C, Green KY. Immunogenicity and specificity of norovirus Consensus GII.4 virus-like particles in monovalent and bivalent vaccine formulations. Vaccine 30: 3580-3586, 2012. Parrino TA, Schreiber DS, Trier JS, Kapikian AZ, Blacklow, NR. Clinical immunity in acute gastroenteritis caused by Norwalk agent. N Engl J Med 297: 86-89, 1977. Paton EJA, Coutinho MA, Voltarelli JC. Diagnóstico e tratamento de complicações agudas do transplante de células progenitoras hematopoiéticas. Medicina Ribeirão Preto 33: 264-277, 2000. Phillips G, Lopman B, Tam CC, Iturriza-Gomara M, Brown D, Gray J. Diagnosing norovírus-associated infectious intestinal disease using viral load. BMC Infect Dis 9: 63, 2009. Prasad BV, Hardy ME, Dokland T, Bella J, Rossmann MG, Estes MK. X-ray crystallographic structure of the Norwalk virus capsid. Science 286: 287-290, 1999. Richardson C, Bargatze RF, Goodwin R, Mendelman PM. Norovirus virus-like particle vaccines for the prevention of acute gastroenteritis. Expert Rev Vaccines 12(2):155-167, 2013. Robles JDF, Cheuk DKL, HaSY, Chiang AKS, Chan GCF. Norovirus Infection in Pediatric Hematopoietic Stem Cell Transplantation Recipients: Incidence, Risk, Factors, and Outcome. Am Soc for Blood and Marrow Transp 18: 1883-1889, 2012. 66 Rockx B, De Wit M, Vennema H, Vinjé J, De Bruin E, Van Duynhoven Y, Koopmans M. Natural history of human calicivirus infection: a prospective cohort study. Clin Infect Dis 35: 246-253, 2002. Roddie C, Paul JPV, Benjamin R, Gallimore CI, Xerry J, Gray JJ, Peggs K S, Morris EC, Thomson KJ, Ward KN. Allogeneic hematopoietic stem cell transplantation and norovirus gastroenteritis: a previously unrecognized cause of morbidity. Infect Dis Society of America 49: 1061-1068, 2009. Roos-Weil D, Ambert-Balay K, Lanternier F, Mamzer-Bruneel MF, Nochy D, Pothier P, Avettand-Fenoel V, Anglicheau D, Snanoudj R, Bererhi L, Thervet E, Lecuit M, Legendre C, Lortholary O, Zuber J. Impact of norovirus/sapovirus-related diarrhea in renal transplant recipients hospitalized for diarrhea. Transplantation 92: 61-69, 2011. Rossignol JF, El-Gohary YM. Nitazoxanide in the treatment of viral gastroenteritis: a randomized double-blind placebo-controlled clinical trial. Aliment Pharmacol Ther 24: 1423-1430, 2006. Rynans S, Dzieciątkowski T, Młynarczyk G. Adenovirus infection in immunocompromised patients. Postepy Hig Med Dosw 67: 964-972, 2013. Sai L, Wang G, Shao L, Liu H, Zhang Y, Qu C, Ma L. Clinical and molecular epidemiology of norovirus infection in adults with acute gastroenteritis in Ji'nan, China. Arch Virol 158(11): 2315-2322, 2013. Saif MA, Bonney DK, Bigger B, Forsythe L, Williams N, Page J, Babiker ZO, Guiver M, Turner AJ, Huges S, Wynn RF. Chronic norovírus infection in pediatric hematopoietic stem cell transplant recipients: A cause of prolonged intestinal failure requiring intensive nutritional support. Pediatri Transplantation 15: 505-509, 2011. Schalk, E, Geginat G, Schulz C, Schlüter D, Fischer T. The incidence of norovírus infections in cancer patients show less seasonal variability compared to patients with other diseases. Ann Hematol, letter to the editor, 2013. Schorn R, Höhne M, Meerbach A, Bossart W, Wüthrich RP, Schreier E, Müller NJ, Fehr T. Chronic norovirus infection after kidney transplantation: molecular evidence for immune- driven viral evolution. Clin Infect Dis 51: 307-314, 2010. Schwartz S, Vergoulidou M, Schreier E, Loddenkemper C, Reinwald M, Scmidt- Hieber M, Flegel WA, Thiel E, Schenider T. Norovirus gastroenteritis causes severe and lethal complications after chemotherapy and hematopoietic stem cell transplantation. Blood 117: 5850-5856, 2011. Seah EL, Marshall JA, Wright PJ. Trans activity of the norovirus Camberwell proteinase and cleavage of the N- terminal protein encoded by ORF1. J Virol 77: 11790-11797, 2003. 67 Sestak K, Feel S, Fey B, Dufour J, Hargitt E, Alvarez X, Pahar B, Gregoricus N, Vinje J, Farkas T. Experimental inoculation of juvenile Rhesus Macaques with primate enteric caliciviruses. PLoS ONE 7: e37973, 2012. Shimizu H, Phan TG, Nishimura S, Okitsu S, Maneekarn N, Ushijima H. An outbreak of adenovirus serotype 41 infection in infants and children with acute gastroenteritis in Maizuru City, Japan. Infect Genet Evol 7: 279-284, 2007. Shimizu-Onda Y, Akasaka T, Yagyu F, Komine-Aizawa S, Tohya Y, Hayakawa S, Ushijima H. The virucidal effect against murine norovirus and feline calicivirus as surrogates for human norovirus by ethanol-based sanitizers. J Infect Chemother 19(4): 779-781, 2013. Sickbert-Bennett EE, Weber DJ, Gergen-Teague MF, Sobsey MD, Samsa GP, Rutala WA. Comparative efficacy of hand hygiene agents in the reduction of bacteria and viruses. Am J Infect Control 33: 67-77, 2005. Siddiq DM, Koo HL, Adachi JA, Viola GM. Norovirus gastroenteritis successfully treated with nitazoxanide. J Infect. 63(5): 394-397, 2011. Siebenga JJ, Vennema H, Duizer E, Koopmans MP. Gastroenteritis caused by norovirus GGII.4, the Netherlands, 1994–2005. Emerg Infect Dis 13: 144-146, 2007. Siebenga JJ, Beersma MF, Vennema H, van Biezen P, Hartwig NJ, Koopmans M. High prevalence of prolonged norovirus shedding and illness among hospitalized patients: a model for in vivo molecular evolution. J infect Dis 198: 994-1001, 2008. Siebenga JJ, Vennema H, Zheng DP, Vinjé J, Lee BE, Pang XL, Ho EC, Lim W, Choudekar A, Broor S, Halperin T, Rasool NB, Hewitt J, Greening GE, Jin M, Duan ZJ, Lucero Y, O'Ryan M, Hoehne M, Schreier E, Ratcliff RM, White PA, Iritani N, Reuter G, Koopmans M. Norovirus illness is a global problem: emergence and spread of Norovirus GII.4 Variants. J Infect Dis 200: 802-812, 2009. Simmons K, Gambhir M, Leon J, Lopman B. Duration of Immunity to Norovirus Gastroenteritis. Emerg Infect Dis 19: 1260-1267, 2013. Sosnovtsev SV, Green KY. Identification and genomic mapping of the ORF3 and VPg proteins in feline calicivirus virions. Virology 277: 193-203, 2000. Souza M, Costantini V, Azevedo MSP, Saif LJ. A human norovirus-like particle vaccine adjuvanted with ISCOM or mLT induces cytokine and antibody responses and protection to the homologous GII.4 human norovirus in a gnotobiotic pig disease model. Vaccine 25: 8448-8459, 2007. 68 Sukhrie FH, Beersma MF, Wong A, van der Veer B, Vennema H, Bogerman J, Koopmans M. Using molecular epidemiology to trace transmission of nosocomial norovirus infection. J Clin Microbiol 49: 602-606, 2011. Takanashi S, Hashira S, Matsunaga T, Yoshida A, Shiota T, Tung PG, Khamrin P, Okitsu S, Mizuguchi M, Igarashi T, Ushijima H. Detection, genetic characterization, and quantification of norovirus RNA from sera of children with gastroenteritis. J Clin Virol 44: 161-163, 2009. Tam CC, O'Brien SJ, Tompkins DS, Bolton FJ, Berry L, Dodds J, Choudhury D,Halstead F, Iturriza-Gómara M, Mather K, Rait G, Ridge A, Rodrigues LC, Wain J,Wood B, Gray JJ; IID2 Study Executive Committee. Changes in causes of acute gastroenteritis in the United Kingdom over 15 years: microbiologic findings from 2 prospective, population-based studies of infectious intestinal disease. Clin Infect Dis 54(9):1275-1286, 2012. Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S. MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 28: 2731-2739, 2011. Tan M, Jiang X. The p domain of norovirus capsid protein forms a subviral particle that binds to histo-blood group antigen receptors. J Virol 79: 14017- 14030, 2005. Teunis PF, Moe CL, Liu P, Miller SE, Lindesmith L, Baric RS, Le Pendu J, Calderon RL. Norwalk virus: how infectious is it? J Med Virol 80: 1469-1476, 2008. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. The CLUSTAL X Windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25: 4876-4882, 1997. Thornton AC, Jennings-Conklin KS, McCormick MI. Noroviruses. Agents in outbreaks of acute gastroenteritis. Disaster Manag Response 2: 4-9, 2004 Thorven M, Grahn A, Hedlund KO, Johansson H, Wahlfrid C, Larson G, Svensson L. A homozygous nonsense mutation (428G–.A) in the human secretor (FUT2) gene provides resistance to symptomatic norovirus (GGII) infections. J Virol 79: 15351-15355, 2005. Treanor JJ, Dolin R. Norwalk virus and other caliciviruses. In: Mandell GL, Bennett JE. Principles and practice of infectious diseases. 5th ed. Philadelphia: Churchill Livingstone 2: 1949-1956, 2000. Ushijima H. Diagnosis and molecular epidemiology of viral gastroenteritis in the past, present and future. Uirusu 59(1):75-90, 2009. 69 Vega E, Barclay L, Gregoricus N, Shirley SH, Lee D, Vinjé J. Genotypic and Epidemiologic Trends of Norovirus Outbreaks in the United States, 2009- 2013. J Clin Microbiol, 2013. Verhoef L, Koopmans M, VAN Pelt W, Duizer E, Haagsma J, Werber D, VAN Asten L,Havelaar A. The estimated disease burden of norovirus in The Netherlands. Epidemiol Infect 17: 1-11, 2012. Vicentini F, Denadai W, Gomes YM, Rose TL, Ferreira MSR,Le Moullac V, Le Pendu J, Leite JPG, Miagostovich MP, Spano LC. Molecular Characterization of Noroviruses and HBGA from Infected Quilombola Children in Espirito Santo State, Brazil. PLoS ONE 8(7): e69348, 2013. Vigorito AC, De Souza CA. Transplante de células-tronco hematopoiéticas e a regeneração da hematopoese. Rev Bras Hematol Hemoter 31: 280-284, 2009. Vinjé J, Hamidjaja RA, Sobsey MD. Development and application of a capsid VP1 (region D) based reverse transcription PCR assay for genotyping of genogroup I and II noroviruses. J Virol Methods 116: 109-117, 2004. Vivancos R, Keenan A, Sopwith W, Smith K, Quigley C, Mutton K, Dardamissis E, Nichols G, Harris J, Gallimore C, Verhoef L, Syed Q, Reid J. Norovirus outbreak in a cruise ship sailing around the British Isles: investigation and multi-agency management of an international outbreak. J Infect 60: 478-485, 2010. Wingfield T, Gallimore CI, Xerry J, Gray JJ, Klapper P, Guiver M, Blanchard TJ. Chronic norovirus infection in an HIV-positive patient with persistent diarrhoea: a novel cause. J Clin Virol 49(3): 219-222, 2010. Wobus CE, Thackray LB, Virgin 4th HW. Murine norovirus: a model system to study norovirus biology and pathogenesis. J Virol (80): 5104-5112, 2006. World Health Organization (WHO). Diarrhoeal disease. Key facts. 2009. Disponível em: http://www.who.int/mediacentre/factsheets/fs330/en/index.html. Acesso em 27.12.12. Wyatt RG, Dolin R, Blacklow NR, DuPont HL, Buscho RF, Thornhill TS, Kapikian AZ, Chanock RM. Comparison of three agents of acute infectious nonbacterial gastroenteritis by cross- challenge in volunteers. J Infect Dis 129: 709-714, 1974. Xavier MPTP, Oliveira SA, Ferreira MSR, Victoria M, Miranda V, Silva MFM, Strina A, Barreto ML, Miagostovicht MP, Leite JPG. Detection of calicivírus associated with acute infantile gastroenteritis in Salvador, an urban center in Northeast Brazil. Braz J Biol Res 42: 438-444, 2009. 70 Xi JN, Graham DY, Wang KN, Estes MK. NV genome cloning and characterization. Science 250: 1580-1583, 1990. Yan H, Yagyu F, Okitsu S, NishioI O, Ushijima H. Detection of norovirus (GI, GII), sapovirus and astrovirus in fecal samples using reverse transcription single-round multiplex PCR. J Virol Methods 114: 37-44, 2003. Zhang H, Chen L, Que W. Allogeneic peripheral blood stem cell and bone marrow transplantation for hematologic malignancies: meta-analysis of randomized controlled trials. Leuk Res36: 431-437, 2012. Zheng DP, Ando T, Fankhauser RL, Beard RS, Glass RI, Monroe SS. Norovirus classification and proposed strain nomenclature. Virology 346: 312- 323, 2006. Zheng DP, Widdowson MA, Glass RI, Vinje J. Molecular epidemiology of genogroup II-genotype 4 noroviruses in the United States between 1994 and 2006. J Clin Microbiol 48: 168-177, 2010. |
Page generated in 0.0078 seconds