maria.cristina.rc2690@gmail.com / Article / Introduction: There is limited and controversial information regarding the potential impact of depression on glycemic control. This study aims to evaluate the association between depression and poor glycemic control. In addition, the prevalence of depression and rates of poor glycemic control were determined. Methods: Cross-sectional study performed in the endocrinology unit of two hospitals of ESSALUD in Peru. The outcome of interest was poor glycemic control, evaluated by glycated hemoglobin (HbA1c: < 7% versus ≥ 7%), whereas the exposure of interest was depression defined as 15 or more points in the Patient Health Questionnaire-9 tool. The association of interest was evaluated using Poisson regression models with robust standard errors reporting prevalence ratios (PR) and 95% confidence intervals (95% CI) adjusting for potential confounders. Results: A total of 277 participants, 184 (66.4%) males, mean age 59.0 (SD: 4.8), and 7.1 (SD: 6.8) years of disease were analyzed. Only 31 participants (11.2%; 95% CI: 7.5%–14.9%) had moderately severe or severe depression, whereas 70 (25.3%; 95% CI 20.3%–30.8%) had good glycemic control. Depression increased the probability of having poor glycemic control (PR = 1.32; 95% CI 1.15–1.51) after adjusting for several potential confounders. Conclusions: There is an association between depression and poor glycemic control among type 2 diabetes patients. Our results suggest that early detection of depression might be important to facilitate appropriate glycemic control and avoid further metabolic complications. / We would like to thank Dr Viviana Ulloa who helped us
to access data and T2D patients, and Dr Percy Mayta-
Tristan for revising initial versions of the manuscript.
AB-O is supported by Wellcome Trust Research Training
Fellowship in Public Health and Tropical Medicine (Grant
number 103994/Z/14/Z). / Revisión por pares
Identifer | oai:union.ndltd.org:PERUUPC/oai:repositorioacademico.upc.edu.pe:10757/556689 |
Date | 10 June 2015 |
Creators | Crispín Trebejo, Brenda, Robles Cuadros, María Cristina, Bernabe-Ortiz, Antonio |
Publisher | Wiley Publishing Asia Pty Ltd |
Source Sets | Universidad Peruana de Ciencias Aplicadas (UPC) |
Language | English |
Detected Language | English |
Type | info:eu-repo/semantics/article |
Format | application/pdf |
Source | Universidad Peruana de Ciencias Aplicadas (UPC), Repositorio Académico - UPC |
Rights | info:eu-repo/semantics/openAccess |
Relation | http://www.ncbi.nlm.nih.gov/pubmed/26037488 |
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