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The Acute Impact of a High-Fat Load on PBMCs among Women: The Impact of Ethnicity and Weight Status

Peripheral blood mononuclear cells (PBMCs) can respond to dietary stimuli modulating the up-regulation of pro-inflammatory cell signaling, which is associated with metabolic disease and has been seen to be elevated in African American (AA) when compared to Caucasian American (CA) women. Little is known about the response of PBMCs to a high fat meal among women and the potential impact of ethnicity and/or weight status on this response. The purpose of this study was to examine PBMC response to consuming a high fat meal and the response to culturing PBMCs in media supplemented with lipid among AA and CA women, and to determine the impact that ethnicity and/or weight status may have on this response. Twenty-one women participated in the study: 10 AA (age: 28.00±6.60), 11 CA (age: 26.91±6.28), of whom 11 were lean (BMI

Identiferoai:union.ndltd.org:WKU/oai:digitalcommons.wku.edu:theses-3018
Date01 April 2017
CreatorsPearson, Regis
PublisherTopSCHOLAR®
Source SetsWestern Kentucky University Theses
Detected LanguageEnglish
Typetext
Formatapplication/pdf
SourceMasters Theses & Specialist Projects

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