Gene Regulation at a Distance: Higher-Order Chromatin Folding and the Coordinated Control of Gene Transcription at the Epidermal Differentiation Complex Locus

Description

No / Chromatin structure and spatial interactions between proximal and distal gene regulatory elements, including gene core promoters and enhancers, are important in the control of gene transcription. In this issue, Oh et al. characterized an AP-1-dependent enhancer at the epidermal differentiation complex locus that establishes spatial interactions with numerous gene promoter regions at that locus.

Links & Downloads

1. Fessing, M. Y. (2014) Gene regulation at a distance: higher-order chromatin folding and the coordinated control of gene transcription at the epidermal differentiation complex locus. Journal of Investigative Dermatology, 134 (9) 2307-10
2. http://hdl.handle.net/10454/6831
3. https://doi.org/10.1038/jid.2014.247

Tags

Gene regulation

Higher-order chromatin folding

Gene transcription

Gene regulatory elements

Epidermis

Epidermal Differentiation Complex Locus

Additional Fields

Identifer	oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/6831
Date	January 2014
Creators	Fessing, Michael Y.
Source Sets	Bradford Scholars
Language	English
Detected Language	English
Type	Article, No full-text in the repository