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Assessing the Effects of Bio-identical Hormone Replacement Therapy Using the Menopause Rating Scale

Class of 2006 Abstract / Objectives: To determine the effect of compounded bio-identical hormone replacement therapy (BHRT) on menopause-related quality of life through comparing the results of the Menopause Rating Scale (MRS) before beginning BHRT and seven weeks into BHRT.
Methods: This study used a one group pre-test/post-test design, also known as pre-experimental. Twenty-one patients participating in a BHRT consultation with the pharmacist at Reed’s Compounding Pharmacy completed an MRS at the time of consultation before beginning BHRT. Seven weeks into treatment with BHRT, patients were mailed a second MRS that they were asked to complete and return to the pharmacy.
Results: The average age of the 21 study participants was 54.9±6.3 years. There was a statistically significant reduction in symptom severity for the total MRS and each of the three subscales after seven weeks of treatment with compounded BHRT (p<0.001). Additionally, there were statistically significant reductions in symptom severity related to hot flushes and sweating, sleep problems, depressive mood, irritability, and anxiety (p<0.001). Conclusions: Compounded BHRT is effective in improving menopause-related quality of life in women suffering from menopausal symptoms.

Identiferoai:union.ndltd.org:arizona.edu/oai:arizona.openrepository.com:10150/624463
Date January 2006
CreatorsBehabadi, Shaghayegh
ContributorsReed-Kane, Dana, Draugalis, JoLaine, College of Pharmacy, The University of Arizona
PublisherThe University of Arizona.
Source SetsUniversity of Arizona
Languageen_US
Detected LanguageEnglish
Typetext, Electronic Report
RightsCopyright © is held by the author.

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