<p> Synthetic methods for the preparation of 2,7-dimethoxy-1-naphthoic acid are presented. The selective reduction of this acid with sodium in liquid ammonia to give 1,4-dihydronaphthoic acid is described.</p> <p> The selective Birch reduction of 2,7-dimethoxynaphthalene to 1,4-dihydro-2,7-dimethoxynaphthalene has been accomplished. 2,7-Dimethoxy-3- isopropylnaphthalene was converted to 3-keto-12-methoxy-10-carbomethoxy-13-isopropylperhydrophenanthra-4,8,11,13-tetraene via, 1,2,3,4-tertrahydro-7-methoxy-6-isopropyl-1-carbomethoxynaphthalen-2-one. The transformation of
3-keto-12-methoxy-10-carbomethoxy-13-isopropylperhydrophenanthra-4,8,11,13-
tetraene to methyl O-methyl-11-desoxycarnosate via methylation, thioketalisation,
desulphurisation and hydrogenation is also described.</p> / Thesis / Doctor of Philosophy (PhD)
| Identifer | oai:union.ndltd.org:mcmaster.ca/oai:macsphere.mcmaster.ca:11375/19761 |
| Date | 09 1900 |
| Creators | Oommen, Puthenpurackal Kurian |
| Contributors | Bell, R. A., Chemistry |
| Source Sets | McMaster University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis |
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