Serotonin has been implicated as a modulator of feeding behavior. This experiment was designed to alter brain serotonin levels through dietary means in hypothalamic ventromedial-lesioned and unlesioned rats. Daily food, water, and animal weights were measured. The purpose was to determine if VMH lesions altered the feeding pattern found in unlesioned rats. Although food intake for tryptophanenriched diets and tryptophan-deficient diets did not differ from their respective control groups, in some cases gross animal weights did differ significantly between experimental and control groups and between lesioned and unlesioned groups. A proposed model explains how a "low" energy signal and a "high" protein signal cycles amino acids through gluconeogenesis to comPensate for an energy deficit.
| Identifer | oai:union.ndltd.org:unt.edu/info:ark/67531/metadc504188 |
| Date | 05 1900 |
| Creators | McDermott, Kathy Howard |
| Contributors | Barker, David J., Aschenbrenner, John E., Schafer, Rollie, Orr, Edward Lee |
| Publisher | North Texas State University |
| Source Sets | University of North Texas |
| Language | English |
| Detected Language | English |
| Type | Thesis or Dissertation |
| Format | vii, 95 leaves: ill., Text |
| Rights | Public, McDermott, Kathy Howard, Copyright, Copyright is held by the author, unless otherwise noted. All rights reserved. |
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