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Production of corticosteroids by rat adrenal tissue in vitro.

Replacement therapy provided the first element of knowledge of the nature of adrenocortical secretion. The earliest view on this secretion assumed the existence of a single adrenocortical hormone, called "cortin" (5}. Attempts were made to extract, isolate and characterize this principle from the adrenals. ROGOFF et al. round that aqueous extracts of adrenal tissue have the property of maintaining life in adrenaleotomized animals. ( 6) SWINGLE et al. in 1931 (7) demonstrated unequivocally that the fraction soluble in usual lipid solvents possesses a far greater potency.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.110323
Date January 1956
CreatorsStachenko, Janine. L.
ContributorsVenning, E. (Supervisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageMaster of Science. (Department of Health Sciences.)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: NNNNNNNNN, Theses scanned by McGill Library.

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