Gnathic changes after head and neck radiotherapy have not been thoroughly characterized radiographically. The objectives of this study are to characterize changes to the teeth and jaws on panoramic images following intensity modulated radiotherapy (IMRT), and to determine whether subject comorbidities and radiation dose affect these changes. This retrospective analysis reviews the charts and panoramic images of 126 head and neck cancer patients who received IMRT at Princess Margaret Hospital between January 1, 2005 and December 31, 2008. Of the 126 subjects, 75 (60%) showed changes on panoramic radiographs; 66 (88%) of which consisted of widened periodontal ligament spaces (WPLS). The median time to WPLS was 29 months after IMRT. Female sex and dose correlated with decreased time to WPLS. These results suggest that WPLS is a common radiographic sign following IMRT that may not require endodontic intervention as post-IMRT WPLS is unrelated to the pulpal status of the tooth.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:OTU.1807/33363 |
| Date | 21 November 2012 |
| Creators | Chan, King Chong |
| Contributors | Pharoah, Michael John |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | en_ca |
| Detected Language | English |
| Type | Thesis |
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