<p>The purpose of the study was to:</p><p>• Study the effect of vascular gas bubbles on the brain and lung</p><p>• Study changes in the endothelial function caused by gas bubbles</p><p>• Study the preventive effects of monoclonal anti-C5a antibody on functional changes caused by gas bubbles</p><p>It is important to reveal any changes in the function of the endothelium caused by gas bubbles, as the endothelium probably plays an important role in the development of decompression sickness (DCS). Furthermore, we followed up previous studies using monoclonal anti-C5a antibody trying to prevent damages caused by gas bubbles. In order to prevent damages causes by gas bubbles and maybe prevent DCS, the mechanisms behind have to be revealed. This thesis is part of an ongoing project that for several years has tried to bring to light the “secrets” of DCS. </p>
| Identifer | oai:union.ndltd.org:UPSALLA/oai:DiVA.org:ntnu-347 |
| Date | January 2003 |
| Creators | Nossum, Vibeke |
| Publisher | Norwegian University of Science and Technology, Department of Circulation and Medical Imaging, Det medisinske fakultet |
| Source Sets | DiVA Archive at Upsalla University |
| Language | English |
| Detected Language | English |
| Type | Doctoral thesis, comprehensive summary, text |
| Relation | Dissertations at the Faculty of Medicine, ; 227 |
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