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Transition metals as anti-tumoral agents: some structure-function relationships of the platinum group metals

<p>Since the discovery that cis-diamminedichloroplatinum (II) possessed great antitumor properties, researchers have been synthesizing and screening metal coordination complexes for their potential anti-tumor activity. Hundreds of compounds have been tested, and few compounds possessed anti-tumor activity. This paper examines how the physical and chemical properties of complexes of the platinum group metals affect their toxicity and anti-tumor activity.</p> / Master of Science

Identiferoai:union.ndltd.org:VTETD/oai:vtechworks.lib.vt.edu:10919/41305
Date02 March 2010
CreatorsFlynn, Allison
ContributorsChemistry, Merola, Joseph S., Niehaus, Walter G. Jr., Brewer, Karen J.
PublisherVirginia Tech
Source SetsVirginia Tech Theses and Dissertation
Detected LanguageEnglish
TypeMaster's project
FormatBTD, application/pdf
RelationLD5655.V851_1994.F596.pdf

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