This thesis concerns the estimation of extreme quantiles on a dose-response curve. It focuses on the Robbins-Monro and up-and-down procedures. Simulation studies run in search of the LD15 and LD30 using a variety of methods suggest that the Robbins-Monro procedure is optimal in terms of Monte Carlo MSE and bias. The up-and-down procedure's performance differs in many cases only slightly from that of the Robbins-Monro process, therefore indicating its value as a practical alternative to the Robbins-Monro process for extreme-quantile estimation.
Identifer | oai:union.ndltd.org:vcu.edu/oai:scholarscompass.vcu.edu:etd-5434 |
Date | 01 January 1997 |
Creators | Bettendorf, Daniel |
Publisher | VCU Scholars Compass |
Source Sets | Virginia Commonwealth University |
Detected Language | English |
Type | text |
Format | application/pdf |
Source | Theses and Dissertations |
Rights | © The Author |
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