by Huichang Zhang. / Thesis (Ph.D.)--Chinese University of Hong Kong, 1996. / Includes bibliographical references (leaves 114-130). / Acknowledgment --- p.i / Abstract --- p.ii / Abbreviations --- p.iii / Table of Contents --- p.iv-v / Chapter Chapter I --- Introduction --- p.1 / Chapter I --- The basis of asymmetric catalysis --- p.6 / Chapter II --- Chiral catalyst --- p.8 / Chapter II-I --- Center metal --- p.9 / Chapter II-II --- Chiral ligand --- p.10 / Chapter III --- Structural analysis of effective chiral ligands --- p.13 / Chapter III-I --- Monodentate ligand --- p.15 / Chapter III-II --- Bidentate Ligand --- p.16 / Chapter 1 --- Bidentate phosphine ligand --- p.16 / Chapter 2 --- Bidentate oxygen ligand --- p.17 / Chapter 3 --- Bidentate nitrogen ligand --- p.19 / Chapter 4 --- "Bidentate ligand with N, 0，P, or S donor atom" --- p.21 / Chapter III-III --- Potentially tridentate ligand --- p.22 / Chapter III-IV --- Potentially tetradentate ligand --- p.23 / Chapter IV --- Tentative conclusions on the effect of structural elements --- p.24 / Chapter Chapter II --- "Design, synthesis and resolution of novel chiral pyridylphenols" --- p.27 / Chapter I --- Design of chiral ligand --- p.27 / Chapter II --- Synthesis of chiral ligands --- p.29 / Chapter II-I --- "Synthesis of the chiral N, O-donor ligands" --- p.29 / Chapter 1 --- Synthesis of the chiral ligands 75a-75c --- p.29 / Chapter 2 --- Synthesis of the chiral ligands 93a and 93b --- p.37 / Chapter 3 --- Synthesis of the chiral ligands 97a-97c --- p.41 / Chapter II-II --- "Synthesis of the chiral N, P-donor ligand 98 and N, S-donor ligand 101" --- p.42 / Chapter III --- Resolution of racemates of chiral ligands --- p.44 / Chapter III-I --- Resolution of of the pyridylphenol 75b --- p.44 / Chapter III-II --- Resolution of of the pyridylphenol 93a --- p.48 / Chapter III-III --- Racemization study of 75b and 93a --- p.52 / Chapter 1 --- Racemization test of 75b --- p.52 / Chapter 2 --- Racemization test of 93a --- p.52 / Chapter Chapter III --- Asymmetric addition of diethylzinc to aromatic aldehydes catalyzed by chiral pyridylphenols / Chapter I --- Backgound --- p.53 / Chapter II --- Asmmetric addition of Et2Zn to aldehydes catalyzed by chiral pyridylphenols --- p.61 / Chapter II-I --- Asmmetric addition of Et2Zn to aldehydes catalyzed by (R)-(+)-75b --- p.61 / Chapter 1 --- The influence of the solvent --- p.61 / Chapter 2 --- The influence of the reaction temperature --- p.64 / Chapter 3 --- The influence of the concentration of catalyst --- p.66 / Chapter 4 --- Electronic effect on the enantioselectivity of asymmetric addition of Et2Zn to aromatic aldehydes --- p.67 / Chapter II-II --- Asmmetric addition of Et2Zn to aldehydes catalyzed by (5)-(+)-75b --- p.73 / Chapter II-III --- Asmmetric addition of Et2Zn to aldehydes catalyzed by (R)-(+)-93a --- p.75 / Chapter III --- Conclusions --- p.78 / Chapter Chapter V --- Experimental Section --- p.79 / References --- p.114 / NMR Spectra --- p.131
| Identifer | oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_322585 |
| Date | January 1996 |
| Contributors | Zhang, Huichang., Chinese University of Hong Kong Graduate School. Division of Chemistry. |
| Source Sets | The Chinese University of Hong Kong |
| Language | English |
| Detected Language | English |
| Type | Text, bibliography |
| Format | print, v, 186 leaves : ill. ; 30 cm. |
| Rights | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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