The purpose of this study was to determine if maximal aerobic exercise promotes
BDNF expression in obese individuals. Plasma levels and the expression of BDNF in
PBMCs were examined. 22 participants (10 obese, 12 non-obese) completed a V02max
treadmill test and blood was obtained pre, post, and 1 and 2 hours into exercise recovery.
Plasma and PBMCs were isolated and analyzed for BDNF via ELISA and Western blot
techniques. A significant effect for time was observed for plasma BDNF (P= <0.00 1 ).
Additionally, A significant group-by-time interaction was found from pre-to-RIH for
BDNF expression in PBMCs (P= 0.046). Further, significant correlations were found
between BMI and waist circumference (r= .91, P< 0.001), WHR (r= .51, P= 0.002) and
Pre-to-RlH ratio (r=0.58, P=0.008). Young obese subject's BDNF response to maximal
exercise was consistent with previous studies. Post-exercise BDNF expressed in PBMCs
were significantly higher than rest suggesting immunological-neuroprotective
interactions in the CNS. / Includes bibliography. / Thesis (M.S.)--Florida Atlantic University, 2016. / FAU Electronic Theses and Dissertations Collection
| Identifer | oai:union.ndltd.org:fau.edu/oai:fau.digital.flvc.org:fau_33701 |
| Contributors | Maharaj, Arun (author), Whitehurst, Michael (Thesis advisor), Florida Atlantic University (Degree grantor), College of Education, Department of Exercise Science and Health Promotion |
| Publisher | Florida Atlantic University |
| Source Sets | Florida Atlantic University |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation, Text |
| Format | 58 p., application/pdf |
| Rights | Copyright © is held by the author, with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder., http://rightsstatements.org/vocab/InC/1.0/ |
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