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Experimental Designs for Generalized Linear Models and Functional Magnetic Resonance Imaging

abstract: In this era of fast computational machines and new optimization algorithms, there have been great advances in Experimental Designs. We focus our research on design issues in generalized linear models (GLMs) and functional magnetic resonance imaging(fMRI). The first part of our research is on tackling the challenging problem of constructing

exact designs for GLMs, that are robust against parameter, link and model

uncertainties by improving an existing algorithm and providing a new one, based on using a continuous particle swarm optimization (PSO) and spectral clustering. The proposed algorithm is sufficiently versatile to accomodate most popular design selection criteria, and we concentrate on providing robust designs for GLMs, using the D and A optimality criterion. The second part of our research is on providing an algorithm

that is a faster alternative to a recently proposed genetic algorithm (GA) to construct optimal designs for fMRI studies. Our algorithm is built upon a discrete version of the PSO. / Dissertation/Thesis / Doctoral Dissertation Statistics 2014

Identiferoai:union.ndltd.org:asu.edu/item:27465
Date January 2014
ContributorsTemkit, M'Hamed (Author), Kao, Jason (Advisor), Reiser, Mark (Committee member), Barber, Jarrett (Committee member), Montgomery, Douglas C (Committee member), Pan, Rong (Committee member), Arizona State University (Publisher)
Source SetsArizona State University
LanguageEnglish
Detected LanguageEnglish
TypeDoctoral Dissertation
Format82 pages
Rightshttp://rightsstatements.org/vocab/InC/1.0/, All Rights Reserved

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