Thesis (MScPhysio)--Stellenbosch University, 2008. / ENGLISH ABSTRACT: Acute exacerbation is an important event of COPD as it causes significant disability and
mortality. Especially repeated hospitalisation of patients with acute exacerbation has been
associated with reduce quality of life and excessive hospitalisation cost. Chronic Obstructive
Pulmonary Disease causes significant functional limitations that translate into enormous
economic and societal burden.
Study Aim: To describe the profile and selected outcomes of Chronic Obstructive Pulmonary
Disease (COPD) patients admitted with acute exacerbation to hospitals in the northern
suburbs of the Western Cape.
Study design: A multicenter retrospective descriptive single subject design was used.
Method: Patients admitted with the diagnosis of COPD with acute exacerbation in the time
period 01June 2004-01June 2005 were followed up retrospectively for a period of 12 months.
The demographics, medical condition on admission and past presentation of acute
exacerbation, length of stay in hospital and the number of readmissions for acute
exacerbation in the 12 month period were collected and recorded on a self designed data
capture sheet.
Results: One hundred and seventy eight patients were admitted with acute exacerbation at
the three hospitals. The mean age of the patients were 63 (±11.73), more males than females
(103: 75) were admitted. Subjects spent a mean of 5.67 (±6.55), days in hospital with every admission and admission frequency of up to eight periods were recorded. Of the n=178
admitted, 56% had one admission and 44% had 2 or more admissions in the study year. This
resulted in a total of 338 hospital admissions with the 78 subjects responsible for the majority
of admissions (238) Subjects presenting with two or more co-morbidities had a significantly
greater risk of multiple re admissions. Subjects with three or more admissions had two or
more co morbidities (p=0.001), comparatively those with one admission had only one co
morbidity. Congestive cardiac failure (p=0.01) as well as the lack of Long Term Oxygen
Therapy p=0.017) were associated with increase risk of three or more admissions.
Conclusion: Patients admitted with acute exacerbation to the hospitals where the study was
conducted presented with an age ranging from 30-95 years. Patients with 2 or more
admissions experience up to eight readmissions episodes in the study year. This is a cause of
concern in respect of the burden of disease on especially the younger economically viable
South African population. In the current study factors that influenced readmission were the
presence of two or more co morbid diseases, specifically the presence of congestive cardiac
failure as well as the lack of LTOT. Interventions including a pulmonary rehabilitation
programme post discharge should be aimed at decreasing frequency of hospitalisation
especially in those patients who are a risk of readmission. / AFRIKAANSE OPSOMMING: Verergering van simptome in Kroniese Obstruktiewe Lugweg Siekte (KOLS) is baie belangrik
as gevolg van die ongeskiktheid en mortalitieit wat dit veroorsaak. Dit veroorsaak
vermindering in die kwaliteit van lewe en verhoog hospitaal koste verbind met die siekte. Die
beperkings toe te skrywe aan die Kroniese Obstruktiewe Lugweg Siekte veroorsaak
ontsettende ekonomiese en sosiale druk.
Doelstelling: Om die profiel en geselekteerde uitkomste van pasiente met Kroniese
Obstruktiewe Lugweg Siekte toegelaat met verergering in die hospitale van die noordelike
voorstede van die Wes Kaap te beskryf.
Studie ontwerp: ʼn Multisentrum retrospektiewe beskrywende enkel persoon studie.
Studie metode: Pasiente toegelaat met verergering van Kroniese Obstruktiewe Lugweg
Siekte in die periode 01Junie 2004-01Junie 2005 was retrospektief opgevolg vir ‘n periode
van 12-maande. Demografiese data, mediese toestand op toelating en ontslag, lengte van
hospitaal verblyf en getal toelatings in die 12- maande was gekollekteer en gedokumenteer
op self ontwerpde vorms.
Resultate: Een-honderd agt en seventig pasiente was toegelaat met verergering by die drie
hospitale. Die gemiddelde ouderdom van die studie populasie was 63 (±11.73) met meer
mans as vrouens (103: 75) toegelaat. Die studie populasie het gemiddelde dae van 5.67
(±6.55), in die hospitaal deurgebring en toelating frekwensie van agt episodes was
gedokumenteer. Van die n=178 toegelaat was 56% eenkeer toegelaat en 44% het 2 of meer toelatings in die studie jaar gehad. Dit het in 338 hospital toelaatings veroorsaak en 78 van
die studie populasie verantwoordelik vir die meeste van die toelatings (238). Die groep met
drie of meer toelatings in die studie jaar het twee of meer siektetoestande (p=0.001) gehad,
teenorgesteld met die wat net een toelaat was met een siektetoestand. Hart versaaking
(p=0.01) en die gebrek aan suurstof by die huis (p=0.017) was verbind met meer risiko van
drie of meer toelating.
Samevatting: Die ouderdoms verskil was wydbeskrywend van 30-95 jaar van die pasiente
wat in die studie jaar toegelaat is by die drie hospitale. Pasiente wat 2 of meer keer toegelaat
is het tot agt hertoelatings in die studie jaar gehad. Kommerwekkend is die uitwerking van die
siekte op die jonger werkend populasie in Suid Afrika. In die studie was hertoelating beinvloed
deur die teenwoordigheid van twee of meer siektetoestande, spesifiek hart versaaking sowel
as die gebrek aan suurstof by die huis. Intervensies insluitende pulmonale rehabilitasie na
ontslag se doel moet wees om vermindering van heraaldelike hospitalisasie in hoë risiko
pasiente vir hospitalisasie.
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:sun/oai:scholar.sun.ac.za:10019.1/21897 |
| Date | 03 1900 |
| Creators | Pienaar, Lunelle Lanine |
| Contributors | Hanekom, S., Unger, M., Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Interdisciplinary Health Sciences. Physiotherapy. |
| Publisher | Stellenbosch : Stellenbosch University |
| Source Sets | South African National ETD Portal |
| Language | en_ZA |
| Detected Language | English |
| Type | Thesis |
| Format | xiv, 107 leaves : ill. |
| Rights | Stellenbosch University |
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