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The Microbiome-Gut-Brain Axis and Alcohol Use Disorder in Adolescents Transitioning into Adulthood

Research on adolescent drinking shows that younger people are at greater risk of developing behavioral deficiencies that can be detrimental to their social relationships and health over time. Recent research has shown that changes within the microbiome-gut-brain axis (MGB) can affect social behavior. These changes involve microbiota populations that influence addictive behaviors after prolonged substance intake through neurochemical shifts that extend through the nervous, circulatory, and immune system. Using Massey's biosocial model, I aim to expand on the relationship between the MGB axis, social behavior, and adolescent alcohol use disorder through a meta-theoretical approach. I explore the strengths and shortcomings of Massey's biosocial model of segregation and stratification and its use of the allostatic load model, telomere length, and gene exposure to develop a stronger theoretical concept using the micro-gut-brain axis as a conceptual foundation. Can the MGB-axis model be used to identify potential pathways in which alcohol use disorder (AUD) persists from adolescence to adulthood? I find that adolescent drinking leads to changes in microbiota populations that are known to influence AUDs and increases the development of diseases such as liver disease and its effects on social behavior. The MGB axis can help us understand the effects of substance and dietary habits on disease and illness by connecting life science knowledge and sociological perspectives. With this modern application of cognitive sociology, I have shown that future research on addictive behaviors should consider the application of biomarker data to further expand on new theoretical and methodological approaches in the study of disease and addiction.

Identiferoai:union.ndltd.org:unt.edu/info:ark/67531/metadc2332618
Date05 1900
CreatorsSandoval Hernandez, Pablo
ContributorsIgnatow, Gabriel, McCaffree, Kevin, NiƱo, Michael
PublisherUniversity of North Texas
Source SetsUniversity of North Texas
LanguageEnglish
Detected LanguageEnglish
TypeThesis or Dissertation
FormatText
RightsPublic, Sandoval Hernandez, Pablo, Copyright, Copyright is held by the author, unless otherwise noted. All rights Reserved.

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