A dissertation submitted to the Faculty of Medicine University of the Witwatersrand, Johannesburg for the degree of Doctor of Philosophy in Medicine
Johannesburg, 1988 / The purpose of this thesis was to investigate the value in clinical situations of the well known in vitro anti-adrenergic effects of magnesium. Research interest in magnesium has been growing rapidly over the last twenty years. However, most of this interest has focused on the clinical consequences of magnesium deficiency states and little attention has been given to magnesium as a therapeutic agent. Despite the wide use of infusions of magnesium sulphate in obstetric practice, there is a dearth of knowledge regarding the actions of magnesium on a cardiovascular system. In laboratory studies, magnesium was shown to inhibit the release of catecholamines from adrenergic nerve terminals, an action which might have great clinical implications. / IT2018
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:wits/oai:wiredspace.wits.ac.za:10539/25808 |
| Date | 23 August 1988 |
| Creators | James, Michael, Frank, Mansel |
| Source Sets | South African National ETD Portal |
| Language | English |
| Detected Language | English |
| Type | Thesis |
| Format | application/pdf |
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