Human behavior plays an important role in infectious disease epidemics. The choice of preventive actions taken by individuals can completely change the epidemic outcome. Computational epidemiologists usually employ large-scale agent-based simulations of human populations to study disease outbreaks and assess intervention strategies. Such simulations rarely take into account the decision-making process of human beings when it comes to preventive behaviors. Absence of realistic agent behavior can undermine the reliability of insights generated by such simulations and might make them ill-suited for informing public health policies. In this thesis, we address this problem by developing a methodology to create and calibrate an agent decision-making model for a large multi-agent simulation, in a data driven way. Our method optimizes a cost vector associated with the various behaviors to match the behavior distributions observed in a detailed survey of human behaviors during influenza outbreaks. Our approach is a data-driven way of incorporating decision making for agents in large-scale epidemic simulations. / Master of Science / In the real world, individuals can decide to adopt certain behaviors that reduce their chances of contracting a disease. For example, using hand sanitizers can reduce an individual‘s chances of getting infected by influenza. These behavioral decisions, when taken by many individuals in the population, can completely change the course of the disease. Such behavioral decision-making is generally not considered during in-silico simulations of infectious diseases. In this thesis, we address this problem by developing a methodology to create and calibrate a decision making model that can be used by agents (i.e., synthetic representations of humans in simulations) in a data driven way. Our method also finds a cost associated with such behaviors and matches the distribution of behavior observed in the real world with that observed in a survey. Our approach is a data-driven way of incorporating decision making for agents in large-scale epidemic simulations.
| Identifer | oai:union.ndltd.org:VTETD/oai:vtechworks.lib.vt.edu:10919/87050 |
| Date | 25 January 2019 |
| Creators | Singh, Meghendra |
| Contributors | Computer Science, Marathe, Madhav Vishnu, Swarup, Samarth, Vullikanti, Anil Kumar S., Mitra, Tanushree |
| Publisher | Virginia Tech |
| Source Sets | Virginia Tech Theses and Dissertation |
| Detected Language | English |
| Type | Thesis |
| Format | ETD, application/pdf |
| Rights | In Copyright, http://rightsstatements.org/vocab/InC/1.0/ |
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