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Memory modulation produced by post-training exposure to an aversive conditioned stimulus

Separate groups of rats were trained to enter one arm of a Y-Maze for food. They were then exposed to footshock, cues previously paired with footshock (CS), or neutral cues. When tested on the Y-Maze 24 hours later, rats that received post-training shock exhibited improved performance compared to rats that received no shock. Immediate post-training CS exposure improved performance compared to rats that were previously shocked but exposed to neutral cues as the post-training treatment. Delayed (2 hours) post-training presentation of the CS did not improve Y-Maze performance compared to immediate post-training presentation of the CS. Post-training exposure to the individual CSs (context or tone) improved Y-Maze performance relative to the neutral cues but not to the combination of cues. / Conditioned freezing and place avoidance in the presence of the CS were two other conditioned responses measured. No correlation was found between any of the responses measured. These findings suggest that conditioned "fear" (an internal affective state) may function independently from observable behavioral measures.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.30666
Date January 1999
CreatorsHolahan, Matthew R.
ContributorsWhite, Norman M. (advisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageMaster of Science (Department of Psychology.)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: 001744484, proquestno: MQ64370, Theses scanned by UMI/ProQuest.

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