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The molecular diagnosis of Pneumocystis pneumonia in children using nasopharyngeal aspirate samples

Pneumocystis pneumonia (PCP) is an important opportunistic infection caused by thefungus Pneumocystis jirovecii. The incidence of PCP in sub-Saharan Africa is on theincrease. This is due to the progression of the HIV-pandemic and limited access to healthcare facilities, specific highly active anti-retroviral therapy and chemoprophylaxis. It is a major cause of hospitalization and mortality in HIV-infected children with in-hospital case-fatality rates ranging from 20-63%.

Identiferoai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uct/oai:localhost:11427/11754
Date January 2011
CreatorsSamuel, Catherine Mary
ContributorsWhitelaw, Andrew, Corcoran, Craig
PublisherUniversity of Cape Town, Faculty of Health Sciences, Division of Medical Microbiology
Source SetsSouth African National ETD Portal
LanguageEnglish
Detected LanguageEnglish
TypeMaster Thesis, Masters, MMed
Formatapplication/pdf

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