The role of the conserved ASP443 and ASP498 residues in the polymerase and RNase H activities of HIV-1 reverse transcriptase

Description

Submiltted in fulfillment of
the requirements for the
degree of Master of Science in
the faculty of Science,
University of the Witwatersrand,
Johannesburg •
Johannesburg 1993. / The roles of the highly conserved aspartic acid residues found at positions 443 and 498 within the RNase H domain of Human Immunodeficiency Virus type-1 reverse transcription were investigated by the defined substitution of these residues using site-directed
mutagenesis.

[Abbreviated Abstract. Open document to view full version] / MT2016

Links & Downloads

1. Brooksbank, Richard L. (1993) The role of the conserved ASP443 and ASP498 residues in the polymerase and RNase H activities of HIV-1 reverse transcriptase, University of the Witwatersrand, Johannesburg, <http://wiredspace.wits.ac.za/handle/10539/21434>
2. http://hdl.handle.net/10539/21434

Tags

HIV (Viruses)--Enzymes

HIV (Viruses)--Research

AIDS (Disease)--Research.

Medical virology

Medical microbiology

Additional Fields

Identifer	oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:wits/oai:wiredspace.wits.ac.za:10539/21434
Date	January 1993
Creators	Brooksbank, Richard L
Source Sets	South African National ETD Portal
Language	English
Detected Language	English
Type	Thesis
Format	Online resource (141 leaves), application/pdf