The effect of source of dietary carboyhydrate upon the concentration
and distribution of phospholipids in the fractions of human
blood was studied. Three healthy women received diets which contained
16% of the calories as protein, 40% as fat, and 44% as carbohydrate.
During the four dietary periods of six days each, 80% of the
carbohydrate was supplied alternately by sucrose (Sugar Diet) or by
polysaccharides from natural sources (Complex Diet). Blood samples
were drawn before breakfast on the final day of each dietary period.
The total lipid, lipid phosphorus, and distribution of phospholipids
were determined in erythrocytes, leukocytes, platelets, and
plasma. Clotting time of the platelet-rich plasma of the subjects
was determined. In periods of this length, no consistent changes in
the blood lipids could be detected. The Sugar Diet appeared to
increase the proportion of phosphatidyl choline and decrease the proportion of sphingomyelin slightly in the plasma and platelets.
The phosphatidyl choline fraction of the leukocyte phospholipids
decreased slightly after the Sugar Diet.
No relationship was observed between in vitro coagulation time
and the distribution of phospholipids in the blood fractions. One
subject did demonstrate a marked increase in coagulation time after
the diet containing complex carbohydrate. / Graduation date: 1969
| Identifer | oai:union.ndltd.org:ORGSU/oai:ir.library.oregonstate.edu:1957/26820 |
| Date | 30 July 1968 |
| Creators | Vesecky, Sharon Ann |
| Contributors | Yearick, Elisabeth S. |
| Source Sets | Oregon State University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
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