Includes abstract. / Includes bibliographical references (leaves 155-181). / Researchers have demonstrated the ability to predict psychopathological states from human peripheral immune tissure transcriptional profiles, using microarrays. Although evidence in support of such an approach as a viable diagnostic avenue within psychiatric settings is accumulating, it remains to be demonstrated, in an animal model, that transcriptional changes in peripheral tissue targets are paralleled by specific gene expression changes in neural tissues.
Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uct/oai:localhost:11427/4347 |
Date | January 2008 |
Creators | Van Heerden, Johannes Hendrik |
Contributors | Illing, Nicola, Stein, Dan |
Publisher | University of Cape Town, Faculty of Science, Department of Molecular and Cell Biology |
Source Sets | South African National ETD Portal |
Language | English |
Detected Language | English |
Type | Master Thesis, Masters, MSc |
Format | application/pdf |
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