Interactions of Asthma Drugs with Artificial Saliva and Mucus. Modeling pulmonary particulate transport requires related biofluid physicochemical properties. Aims included measuring the effects of common aerosol drugs on artificial saliva and diffusivities of asthma medications in mucus. Artificial saliva solutions doped with asthma medications were characterized by pH, interfacial tension, and rheology. To measure diffusion, drug concentration was monitored by time-dependent FTIR spectra, and diffusivity obtained using Fick¡¦s second law. Measured theophylline and albuterol diffusivities were ca. 10-6 cm2/s. Surface Modification of Polymer Films with Light-Emitting Chemicals. To develop a polymer film system that changed color in response to radiation, acid groups of poly(ethylene-co-acrylic acid) were used to attach two light-emitting polymers: 4„S-(octyloxy)-4-biphenylcarboxylic acid and 2,7-bis(bromomethyl)-9,9-dihexyl-9Hluorene. Each reaction step was confirmed using static contact angle goniometry, FTIR spectroscopy, and X-ray photoelectron spectroscopy. UV-Vis and fluorescence spectroscopy measured the absorption spectra. Modified films were irradiated (ƒÜ=254 nm) and produced blue emissions.
| Identifer | oai:union.ndltd.org:MSSTATE/oai:scholarsjunction.msstate.edu:td-5117 |
| Date | 12 May 2012 |
| Creators | Cornell, Ashley Lynn |
| Publisher | Scholars Junction |
| Source Sets | Mississippi State University |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | Theses and Dissertations |
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