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Acute Effects of the Antibiotic Streptomycin on Neural Network Activity and Pharmacological Responses

The purpose of this study is to find out that if antibiotic streptomycin decreases neuronal network activity or affects the pharmacological responses. The experiments in this study were conducted via MEA (multi-electrode array) technology which records neuronal activity from devices that have multiple small electrodes, serve as neural interfaces connecting neurons to electronic circuitry. The result of this study shows that streptomycin lowered the spike production of neuronal network, and also, sensitization was seen when neuronal network pre-exposed to streptomycin.

Identiferoai:union.ndltd.org:unt.edu/info:ark/67531/metadc700026
Date12 1900
CreatorsZeng, Wei Rong
ContributorsGross, Guenter W., Gopal, Kamakshi, Gao, Xiang
PublisherUniversity of North Texas
Source SetsUniversity of North Texas
LanguageEnglish
Detected LanguageEnglish
TypeThesis or Dissertation
Formatvii, 74 pages : illustrations (some color), Text
RightsPublic, Zeng, Wei Rong, Copyright, Copyright is held by the author, unless otherwise noted. All rights reserved.

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