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Synthesis, Purification and Pharacterization of Small Mono(ADP-Ribosyl)ated Molecules in the ADP-Ribose Elongation Reaction Catalyzed by Poly(ADP-ribose)Polymerase

The ADP-ribose elongation catalyzed by poly(ADP-ribose) polymerase (PARP) [EC 2.2.2.30] has been partially characterized utilizing mono (ADP-ribosyl)ated polyamines. Arginine methyl ester (AME)-(ADP-ribose) and agmatine (AGMT)-(ADP-ribose) were synthesized enzymatically with a eukarytic mono(ADP-ribosyl) transferase and cholera toxin, respectively.

Identiferoai:union.ndltd.org:unt.edu/info:ark/67531/metadc798168
Date12 1900
CreatorsPacheco-Rodriguez, Gustavo
PublisherNorth Texas State University
Source SetsUniversity of North Texas
LanguageEnglish
Detected LanguageEnglish
TypeThesis or Dissertation
FormatText
RightsPublic, Copyright, Copyright is held by the author, unless otherwise noted. All rights

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