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RADIOLUMINESCENT NANOPARTICLES FOR MULTIMODAL CANCER TREATMENT

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<p>Conventional clinical therapies for head and neck squamous cell carcinomas (HNSCC) include surgical resection, chemotherapy (CT), and radiotherapy (RT). For locally advanced HNSCC, the CT-RT combination (“chemoradiation”) has been shown to be more effective than CT or RT alone and is the current standard of care. A novel radiation-controlled drug release nanoparticle formulation has been developed to realize the maximum benefits of intratumoral CT-RT. Under the application of low-dose X-ray, the formulation is capable of releasing PTX and providing localized, controlled, and sustained drug release for improvements in therapeutic efficacies.</p>

  1. 10.25394/pgs.20405805.v1
Identiferoai:union.ndltd.org:purdue.edu/oai:figshare.com:article/20405805
Date29 July 2022
CreatorsKaustabh Sarkar (13171509)
Source SetsPurdue University
Detected LanguageEnglish
TypeText, Thesis
RightsCC BY 4.0
Relationhttps://figshare.com/articles/thesis/RADIOLUMINESCENT_NANOPARTICLES_FOR_MULTIMODAL_CANCER_TREATMENT/20405805

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