The objective of this research was the development of a novel synthetic method for preparation of silver/polymer nanocomposites containing finely dispersed silver nanoparticles. The surface of nanosilver was functionalized by amino groups, which then reacted with end acidic groups of polylactide (PLA) and its co-polymer with polyglycolide (PLGA). The condensation reaction was conducted in the presence of diisopropylcarbodiimide. Nanosilver coating with the polymers was confirmed by FT-IR and UV-vis spectroscopy. It was found that not only acid-terminated but also ester-terminated polymers can react with functionalized nanosilver. However, high dispersibility of the nanoparticles was achieved with acid-terminated polymers only. Obtained materials demonstrated X-ray contrast and bactericidal properties that makes possible their prospective application in biology and medicine.
| Identifer | oai:union.ndltd.org:ETSU/oai:dc.etsu.edu:etsu-works-16642 |
| Date | 05 October 2015 |
| Creators | Paul, Anita, Kaverina, Ekaterina, Vasiliev, Aleksey |
| Publisher | Digital Commons @ East Tennessee State University |
| Source Sets | East Tennessee State University |
| Detected Language | English |
| Type | text |
| Source | ETSU Faculty Works |
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