The structure of regional correlation graphs built from fMRI-derived data is frequently used in algorithms to automatically classify brain data. Transformation on the data is performed during pre-processing to remove irrelevant or inaccurate information to ensure that an accurate representation of the subject's resting-state connectivity is attained. Our research suggests and confirms that such pre-processed data still exhibits inherent transitivity, which is expected to obscure the true relationships between regions. This obfuscation prevents known solutions from developing an accurate understanding of a subject’s functional connectivity. By removing correlative transitivity, connectivity between regions is made more specific and automated classification is expected to improve. The task of utilizing fMRI to automatically diagnose Attention Deficit/Hyperactivity Disorder was posed by the ADHD-200 Consortium in a competition to draw in researchers and new ideas from outside of the neuroimaging discipline. Researchers have since worked with the competition dataset to produce ever-increasing detection rates. Our approach was empirically tested with a known solution to this problem to compare processing of treated and untreated data, and the detection rates were shown to improve in all cases with a weighted average increase of 5.88%.
| Identifer | oai:union.ndltd.org:ucf.edu/oai:stars.library.ucf.edu:honorstheses1990-2015-2907 |
| Date | 01 January 2015 |
| Creators | Martinek, Jacob |
| Publisher | STARS |
| Source Sets | University of Central Florida |
| Language | English |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | HIM 1990-2015 |
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