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Assessing the Effects of Bio-identical Hormone Replacement Therapy Using the Menopause Rating Scale

Class of 2008 Abstract / Objectives: The purpose of this study was to assess the effects of using compounded Bio-identical Hormone Replacement Therapy (BHRT) in menopausal women, by employing the MRS.
Methods: This study used a one group pre-test/ post-test. Included were 25 menopausal women, whom at initial BHRT consultation at Reed’s Compounding Pharmacy filled out a baseline menopausal rating scale (MRS). Eleven weeks into therapy, patients were asked to participate in this study and if interest was expressed, they were asked to fill out another MRS for comparison.
Results: There was a statistically significant decrease in overall MRS scores and in each of the 3 subscales (psychological, somatic and urogenital) (p</= 0.001). Additionally, when evaluating each MRS item individually, there were statistically significant decreases in all symptoms of menopause except for heart discomfort. Most improvements were seen in hot flushes/sweating, sleep and sexual problems (p<0.001).
Conclusions: Patients using BHRT improved overall physically and mentally, which would be depicted by improved scores on the MRS.

Identiferoai:union.ndltd.org:arizona.edu/oai:arizona.openrepository.com:10150/624277
Date January 2008
CreatorsBojesen, Christine K.
ContributorsReed-Kane, Dana, Draugalis, JoLaine, College of Pharmacy, The University of Arizona
PublisherThe University of Arizona.
Source SetsUniversity of Arizona
Languageen_US
Detected LanguageEnglish
Typetext, Electronic Report
RightsCopyright © is held by the author.

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