Trata da modelagem teórica de um experimento que simula in vitro a evolução da aptidão (fitness) de uma população de virus. / We consider a nonlinear partial differential equation of conservation type to describe the dy- namics of vesicular stomatitis virus observed in aliquots of fixed particle number taken from an evolving clone at periodic intervals of time [5]. The changes in time behavior of fitness function noticed in experimental data are related to a crossover exhibited by the solutions to this equation in the transient regime for pulse-like initial conditions. As a consequence, the average replication rate of the population is predicted to reach a plateau as a power t1/ 2
| Identifer | oai:union.ndltd.org:usp.br/oai:teses.usp.br:tde-08052014-155647 |
| Date | 03 May 2005 |
| Creators | Carvalhaes, Fernando Goldenstein |
| Contributors | Goldman, Carla |
| Publisher | Biblioteca Digitais de Teses e Dissertações da USP |
| Source Sets | Universidade de São Paulo |
| Language | Portuguese |
| Detected Language | English |
| Type | Dissertação de Mestrado |
| Format | application/pdf |
| Rights | Liberar o conteúdo para acesso público. |
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