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Deployment, Testing and Analysis of Advanced Thermosyphon Target Systems for Production of Aqueous [18F]Fluoride via 18O(p,n)18F

Single phase and boiling batch water targets are the most common designs for the cyclotron production of 18F via the 18O(p,n)18F reaction. Thermosyphon targets have design and operating characteristics which enable higher power operation than conventional boiling targets of like size. Experimental thermosyphon target systems demonstrated the feasibility of high intensity irradiation via bottom pressurized operation. An effective experimental characterization platform was developed and utilized in parallel with computational modeling efforts to further improve designs. A control strategy was also developed to provide a simple and robust means of remote target operation. Clinical production systems were designed and deployed at two facilities.

Identiferoai:union.ndltd.org:NCSU/oai:NCSU:etd-03142008-132437
Date11 April 2008
CreatorsStokely, Matthew Hughes
ContributorsBruce Wieland, M. Bourham, Gerald Bida, Michael Shearer, J. Michael Doster
PublisherNCSU
Source SetsNorth Carolina State University
LanguageEnglish
Detected LanguageEnglish
Typetext
Formatapplication/pdf
Sourcehttp://www.lib.ncsu.edu/theses/available/etd-03142008-132437/
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