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The role of dietary cation-anion difference (DCAD) on the blood buffering capacity and the susceptibility of dairy cattle to induced ketoacidosis /

Two experiments were conducted to investigate the effects of metabolic acid-base balance on feed intake and susceptibility of dairy heifers to ketoacidosis. Animals were fed two dietary cation-anion difference diets [dietary cation-anion difference is defined as mEq (Na++K+)-(Cl -+S2-) kg-1 dietary dry matter], a high dietary cation-anion difference (positive) and a low dietary cation-anion difference (negative). The heifers fed the positive dietary cation-anion difference had significantly higher blood pH, blood bicarbonate and dry matter intake than heifers fed the negative dietary cation-anion difference. There was an initial decrease in dry matter intake by the heifers fed the negative dietary cation-anion difference. However this difference was not significant by the end of the two week period. It is unclear whether the reduced dry matter intake in the heifers fed the negative dietary cation-anion difference is the result of metabolic-acidosis caused by the anionic salts, poor palatability of the anionic salts or a combination of both. Heifers were induced into a nervous ketosis by feeding 1,3-butanediol. There was no difference in the incidence of ketosis between animals fed positive and negative dietary cation-anion difference. Animals fed the positive diet tended to be more susceptible to anorexia.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.30377
Date January 2000
CreatorsFletcher, John D.
ContributorsCue, R. I. (advisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageMaster of Science (Department of Animal Science.)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: 001764889, proquestno: MQ64353, Theses scanned by UMI/ProQuest.

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