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A protocol for constructing a domain-specific ontology for use in biomedical information extraction using lexical-chaining analysis

In order to do more semantics-based information extraction, we require specialized domain models. We develop a hybrid approach for constructing such a domain-specific ontology, which integrates key concepts from the protein-protein–interaction domain with the Gene Ontology. In addition, we present a method for using the domain-specific ontology in a discourse-based analysis module for analyzing full-text articles on protein interactions. The analysis module uses a lexical chaining technique to extract strings of semantically related words that represent the topic structure of the text. We show that the domain-specific ontology improved the performance of the lexical-chaining module. As well the topic structure as represented by the lexical chains contains important information on protein-protein interactions appearing in the same textual context.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:OWTU.10012/2663
Date January 2007
CreatorsHe, Xiaofen
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeThesis or Dissertation
Format1036324 bytes, application/pdf

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