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Analytical Method For Detecting Pcb Derivatives At Low Levels In Surface Water Samples By Solid Phase Extraction-Liquid Chromatography/Mass Spectrometry

Polychlorinated biphenyls (PCBs) and their metabolic derivatives are ubiquitous environmental contaminants. These compounds are of concern because of their persistence and bioaccumulation in nature. PCBs and the hydroxylated metabolites have shown endocrine-disrupting activity. A method of detection in surface water samples is important to identify and quantify the environmental contamination. In this research we have attempted to develop a method of detection. Six representative polychloromethoxybiphenyls (PCMBs) were prepared. The corresponding polychlorobiphenylols, hydroxylated PCB metabolites (OH-PCBs), were prepared from the PCMBs. A method coupling solid phase extraction with liquid chromatography, on-line electrospray ionization, and mass spectrometry (SPE-LC/ESI/MS) was developed for detection of the OH-PCBs in distilled and surface water samples.

Identiferoai:union.ndltd.org:MSSTATE/oai:scholarsjunction.msstate.edu:td-1669
Date07 May 2005
CreatorsAlford, Shannon Recca
PublisherScholars Junction
Source SetsMississippi State University
Detected LanguageEnglish
Typetext
Formatapplication/pdf
SourceTheses and Dissertations

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