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The correlated effects of drugs on coronary flow, heart action and potassium shifts in the isolated perfused rabbit heart.

The sensitivity of the myocardium to alterations in its electrolyte environment has been extensively studied. Danowski and Elkinton (1951) in a detailed review on the effects of potassium on the functions of various organs and systems of the body conclude that "the heart is the most sensitive of all organs to alterations in its extracellular potassium concentration." It is now well established that the concentration of potassium in the extra cellular fluid is low (4 to 5 mEq. per liter in plasma) while the intracellular concentration is considerably higher--approximately 40 mEq. per 100 grams of cat heart tissue (Robertson and Peyser, 1951).

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.110234
Date January 1956
CreatorsKorol, Bernard.
ContributorsMelville, K. (Supervisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageDoctor of Philosophy. (Department of Health Sciences.)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: NNNNNNNNN, Theses scanned by McGill Library.

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