Antagonists have been used for the quantitative measurement of drug interactions with receptors. Using quantitative measurements based on Gaddum's hypothesis (12) that agonists and antagonists compete for receptors according to the mass law, Arunlakshana and Schild (1) have shown that there are remarkable similarities between the effective concentrations of atropine as an acetylcholine antagonist in such widely differing preparations as the guinea pig ileum, guinea pig lung, and chick amnion. It was concluded the receptor for acetylcholine was similar in all three preparations. [...]
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.117819 |
| Date | January 1965 |
| Creators | Hill, Arnold J. |
| Contributors | Benfey, B. (Supervisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science. (Department of Pharmacology. ) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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