The effect of tonicity on the rate and amount of histamine released from several in vitro preparations was studied. In hypertonic (1.2M) solutions of sucrose or mannitol, basic histamine liberators released significantly less histamine from dog liver particles, isolated mast cells, perfused guinea pig lungs, and perfused cat paws, than they did in isotonic solutions. When surface-active compounds were used as histamine liberators, no significant differences were found in the amount of histamine released in the two kinds of solution. [...]
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.112021 |
| Date | January 1959 |
| Creators | McIlreath, Fred J. |
| Contributors | Garcia-Arocha, H (Supervisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Doctor of Philosophy. (Department of Physiology.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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