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Biochemical basis for a genetically determined difference in response to the teratogenic effects of 6-amino-nicotinamide.

The application of precisely timed, short exposures of embryos to specific metabolic inbibitors is a useful method for analysing the biochemical aspects of development. The teratologic approach to the study of the biochemical requirerments of various organogenetic processes in the developing embryo was first formulated by Warkany (1944) who showed that the offspring of female rats maintained on a vitamin A deficient diet had characteristic patterns of malformations. [...]

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.73627
Date January 1966
CreatorsVerrusio, A. Carl
ContributorsFraser, F. (Supervisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageDoctor of Philosophy (Department of Genetics)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: 000455513, proquestno: AAINK00864, Theses scanned by UMI/ProQuest.

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