Return to search

A neuromodula??o do c?rtex pr?-frontal dorsolateral na percep??o de tempo em contexto neutro ou emocionalmente ativo

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-03-22T19:24:32Z
No. of bitstreams: 1
FelipeSantosDeOliveira_TESE.pdf: 1841785 bytes, checksum: 66bb047469f843d38674d96acaa05fd9 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-03-23T20:33:27Z (GMT) No. of bitstreams: 1
FelipeSantosDeOliveira_TESE.pdf: 1841785 bytes, checksum: 66bb047469f843d38674d96acaa05fd9 (MD5) / Made available in DSpace on 2016-03-23T20:33:27Z (GMT). No. of bitstreams: 1
FelipeSantosDeOliveira_TESE.pdf: 1841785 bytes, checksum: 66bb047469f843d38674d96acaa05fd9 (MD5)
Previous issue date: 2014-08-27 / A percep??o temporal ? fundamental para a adapta??o ambiental em humanos e outras esp?-
cies.O processamento temporal nos organismos, se desenvolveu atrav?s de diferentes sistemas
neurais, cada qual respons?vel pelo processamento de diferentes escalas de tempo. Dentre as
escalas mais estudadas,est? a que abrange o arranjo de segundos a minutos. Evid?ncias sugerem
que o c?rtex pr?-frontal dorsolateral (CPFDL) possui rela??o com a percep??o do tempo
na escala de segundos. No entanto, n?o se sabe se o d?ficit de percep??o temporal em pacientes
com les?es cerebrais ou mesmo ?les?es revers?veis? causadas por estimula??o magn?tica transcraniana
(EMT) nessa regi?o, sejam por perturba??es de outros processos cognitivos (como
aten??o e mem?ria de trabalho) ou da percep??o do tempo propriamente dita. Estudos tamb?m
relacionam a regi?o do CPFDL na regula??o emocional e especificamente no julgamento e a
antecipa??o emocional. Diante disto, nosso objetivo foi estudar o papel do c?rtex pr?-frontal
dorsolateral na percep??o de intervalos de tempo de est?mulos neutros e emocionalmente ativos,
a partir dos efeitos da modula??o cortical atrav?s da estimula??o transcraniana por corrente
cont?nua (ETCC), atrav?s da excita??o (corrente an?dica), inibi??o (corrente cat?dica) e o controle
(sham), utilizando os intervalos de 4 e 8 segundos. Nossos resultados mostraram que h?
uma subestimativa quando a figura ? apresentada por 8 segundos.Com a corrente an?dica no
CPFDL direito ocorre uma subestimativa e com a corrente cat?dica no CPFDL esquerdo h?
uma superestimava na reprodu??o do tempo com figuras neutras. Com figuras negativas, a
corrente cat?dica sobre o CPFDL esquerdo ocasiona efeito inverso ao de figuras neutras, havendo
subestimativa de tempo. O uso de figuras com val?ncia positiva ou negativa, melhoraram
as estimativas para 8 segundas e o uso de figuras com val?ncia positiva inibem o efeito da
ETCC no CPFDL na estimativa de tempo para 4 segundos. Com esse trabalho podemos concluir
que o CPFDL tem um papel fundamental na percep??o de tempo e corresponde em grande
parte aos est?gios de mem?ria e decis?o no modelo de rel?gio interno, que o hemisf?rio esquerdo
participa na percep??o de tempo tanto em contextos neutros como emocionalmente
ativos, Podemos concluir tamb?m que a ETCC e um m?todo eficaz para estudar as fun??es
corticais na percep??o de tempo em termos de causa e efeito. / The time perception is critical for environmental adaptation in humans and other species. The
temporal processing, has evolved through different neural systems, each responsible for processing
different time scales. Among the most studied scales is that spans the arrangement of
seconds to minutes. Evidence suggests that the dorsolateral prefrontal (DLPFC) cortex has relationship
with the time perception scale of seconds. However, it is unclear whether the deficit
of time perception in patients with brain injuries or even "reversible lesions" caused by transcranial
magnetic stimulation (TMS) in this region, whether by disruption of other cognitive
processes (such as attention and working memory) or the time perception itself. Studies also
link the region of DLPFC in emotional regulation and specifically the judgment and emotional
anticipation. Given this, our objective was to study the role of the dorsolateral prefrontal cortex
in the time perception intervals of active and emotionally neutral stimuli, from the effects of
cortical modulation by transcranial direct current stimulation (tDCS), through the cortical excitation
(anodic current), inhibition (cathode current) and control (sham) using the ranges of 4
and 8 seconds. Our results showed that there is an underestimation when the picture was presented
by 8 seconds, with the anodic current in the right DLPFC, there is an underestimation
and with cathodic current in the left DLPFC, there is an overestimation of the time reproduction
with neutral ones. The cathodic current over the left DLPFC leads to an inverse effect of neutral
ones, an underestimation of time with negative pictures. Positive or negative pictures improved
estimates for 8 second and positive pictures inhibited the effect of tDCS in DLPFC in estimating
time to 4 seconds. With this work, we conclude that the DLPFC plays a key role in the o
time perception and largely corresponds to the stages of memory and decision on the internal
clock model. The left hemisphere participates in the perception of time in both active and emotionally
neutral contexts, and we can conclude that the ETCC and an effective method to study
the cortical functions in the time perception in terms of cause and effect.

Identiferoai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/20101
Date27 August 2014
CreatorsOliveira, Felipe Santos de
Contributors22800662387, http://lattes.cnpq.br/3347815035685882, Pereira J?nior, Antonio, 25715330297, http://lattes.cnpq.br/3745776950147924, Amorim, Leonardo Gomes de Paiva, 05106687470, http://lattes.cnpq.br/0551544254084113, Miguel, M?rio Andr? Leoc?dio, 29032018892, http://lattes.cnpq.br/9973095281534917, Ferreira, Sionaldo Eduardo, 95230068604, http://lattes.cnpq.br/7730654028676766, Reyes, Marcelo Bussotti, Ara?jo, John Fontenele
PublisherUniversidade Federal do Rio Grande do Norte, PROGRAMA DE P?S-GRADUA??O EM PSICOBIOLOGIA, UFRN, Brasil
Source SetsIBICT Brazilian ETDs
LanguagePortuguese
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/doctoralThesis
Sourcereponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN
Rightsinfo:eu-repo/semantics/openAccess

Page generated in 0.0019 seconds