Ho Cheuk-nang. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2004. / Includes bibliographical references (leaves 89-94). / Abstracts in English and Chinese. / Acknowledge --- p.ii / Table of Contents --- p.iii / Lists of Tables --- p.vi / Lists of Figures --- p.vii / Abstract (English Version) --- p.x / Abstract (Chinese Version) --- p.xii / Chapter 1. --- Literature Survey of Phosphorus Chemical Shift Studies of DNA --- p.1 / Chapter 1.1 --- Introduction --- p.1 / Chapter 1.2 --- General Review of DNA Structures --- p.2 / Chapter 1.2.1 --- "Nomenclature, Symbols and Numbering Scheme" --- p.2 / Chapter 1.2.2 --- Conformations of DNA --- p.7 / Chapter 1.2.3 --- Random Coil State --- p.8 / Chapter 1.3 --- Phosphorus Chemical Shift Studies of DNA --- p.9 / Chapter 1.4 --- Purpose of This Work --- p.10 / Chapter 2. --- Methodology for Studying the Sequence Effect on Random Coil Phosphorus Chemical Shift --- p.12 / Chapter 2.1 --- Introduction --- p.12 / Chapter 2.2 --- Determination of Sequence Effect --- p.12 / Chapter 2.3 --- Design of Sequence --- p.13 / Chapter 2.4 --- Sample Preparation --- p.14 / Chapter 2.5 --- Measurement of Phosphorus Chemical Shift --- p.16 / Chapter 2.5.1 --- Proton Resonance Assignments --- p.16 / Chapter 2.5.2 --- Phosphorus Resonance Assignments --- p.20 / Chapter 2.6 --- Determination of Sugar Conformation --- p.23 / Chapter 2.7 --- Determination of Backbone Conformation --- p.25 / Chapter 3. --- Results and Discussion of Random Coil Phosphorus Chemical Shift of DNA --- p.28 / Chapter 3.1 --- Introduction --- p.28 / Chapter 3.2 --- Resonance Assignments --- p.28 / Chapter 3.3.1 --- Proton Resonance Assignments --- p.31 / Chapter 3.3.2 --- Phosphorus Resonance Assignments --- p.31 / Chapter 3.3 --- Verification of Random Coil State --- p.31 / Chapter 3.2.1 --- Variable Temperature Proton Chemical Shift --- p.31 / Chapter 3.2.2 --- Sugar Conformation --- p.32 / Chapter 3.2.3 --- Backbone Conformation --- p.33 / Chapter 3.4 --- Random Coil Phosphorus Chemical Shift of DNA --- p.33 / Chapter 3.4.1 --- Temperature Effect --- p.33 / Chapter 3.4.2 --- Neighbor Effect --- p.36 / Chapter 3.5 --- Random Coil Phosphorus Chemical Shift Prediction --- p.42 / Chapter 3.5.1 --- Dimer Model Prediction Protocol --- p.42 / Chapter 3.5.2 --- Trimer Model Prediction Protocol --- p.45 / Chapter 4. --- Conclusions and Future Work --- p.48 / Appendix I H6/H8-H1' regions of 2D NOESY spectra of SS1-SS16 --- p.49 / "Appendix II 'H and 31P resonance assignments and 3Jhi1,h2,3Jh1，h2´ح and 3Jh3，p coupling constants of SS1-SS16" --- p.57 / Appendix III H3' regions 1H-31P HSQC spectra of SS1-SS16 --- p.65 / Appendix IV H1，-H2，/H2´حregions of DQF-COSY spectra of SS1- SS16 --- p.73 / Appendix V H3' regions of 1H-31P selective heteronuclear COSY spectra of SS1-SS16 --- p.81 / References --- p.89
| Identifer | oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_324917 |
| Date | January 2004 |
| Contributors | Ho, Cheuk-nang., Chinese University of Hong Kong Graduate School. Division of Chemistry. |
| Source Sets | The Chinese University of Hong Kong |
| Language | English, Chinese |
| Detected Language | English |
| Type | Text, bibliography |
| Format | print, xii, 94 leaves : ill. ; 30 cm. |
| Rights | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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