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Improving the precision and accuracy of Monte Carlo simulation in positron emission tomography

PETSIM, a Monte Carlo simulation program of Positron Emission Tomography (PET) systems, was improved in terms of accuracy and efficiency. First, the accuracy, the speed and the ease of use of PETSIM were improved by using tabulated values of the Compton scattering and photoelectric absorption partial interaction attenuation coefficients for all common biological, collimator and detector materials. These were generated from chemical formula, or physical composition, and density of the absorbing medium. / Furthermore, simulations of PET systems waste considerable time generating events which will never be detected. For events in which the original photons are usually directed towards the detectors, the efficiency of the simulations was improved by giving the photons additional chances of being detected. For simulation programs which cascade the simulation process into source, collimation, and detection phases such as PETSIM, the additional detections resulted in an improvement in the simulation precision without requiring larger files of events from the source/phantom phase of the simulation. This also reduced the simulation time since fewer positron annihilations were needed to achieve a given statistical precision. This was shown to be a useful improvement over conventional Monte Carlo simulations of PET systems.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.68241
Date January 1993
CreatorsPicard, Yani
ContributorsThompson, C. J. (advisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageMaster of Science (Department of Medical Radiation Physics.)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: 001397190, proquestno: AAIMM94499, Theses scanned by UMI/ProQuest.

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