Includes abstract. / Includes bibliographical references (leaves 159-179). / The aims of this dissertation were therefore (i) to follow a pathway-based approach investigating genes encoding proteins involved in the ECM degradation and apoptosis signalling cascade for associations with AT and (ii) to identify a polygenic risk model, comprised of several genetic markers within genes encoding proteins involved in the inflammatory pathway, to predict risk of AT.
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uct/oai:localhost:11427/10807 |
| Date | January 2011 |
| Creators | Nell, Erica-Mari |
| Contributors | September, Alison |
| Publisher | University of Cape Town, Faculty of Health Sciences, MRC/UCT RU for Exercise and Sport Medicine |
| Source Sets | South African National ETD Portal |
| Language | English |
| Detected Language | English |
| Type | Master Thesis, Masters, MSc |
| Format | application/pdf |
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