Significant alterations in the environmental conditions can have pronounced
effects on plant genome stability. Recent evidence argues for a global involvement of the
components of epigenetic modules in the regulation of genome homeostasis both
immediately after stress exposure and long after environmental cues were acquired. The
last observation is of particular interest as the memory of imposing stress can be
maintained at the molecular level throughout plant ontogenesis and may be faithfully
propagated into the following generation. Our study provides evidence that epigenetic
repercussions exerted by stress exposure of parental plants manifest themselves in
untreated progeny at all three levels of the epigenetic module: DNA methylation, histone
posttranslational modifications and small RNA metabolism. Additionally, the results of
our study shed new light on the engagement of the epigenetic machinery in the
maintenance of plant genome integrity by counteracting the activity of invading nucleic
acids. / xv, 280 leaves : ill. ; 29 cm
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:ALU.w.uleth.ca/dspace#10133/3448 |
| Date | January 2013 |
| Creators | Bilichak, Andriy |
| Contributors | Kovalchuk, Igor |
| Publisher | Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, Arts and Science, Department of Biological Sciences |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | en_CA |
| Detected Language | English |
| Type | Thesis |
| Relation | Thesis (University of Lethbridge. Faculty of Arts and Science) |
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